Gene Expression Data
Assay Details
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Assay
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Reference:
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J:143210
Zhou CJ, et al., Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes. Dev Dyn. 2008 Dec;237(12):3681-9
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5554563
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Gene symbol:
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Bmp4
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Gene name:
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bone morphogenetic protein 4
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Probe:
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Bmp4 probe45
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
4A:
embryonic day 10.5
(more  )
Specimen
4A:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
4A
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Expression is in the dorsal neural retina.
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| TS17: head |
Present |
Regionally restricted |
4A
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Expression is in the orofacial processes.
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Specimen
4B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Lrp6Gt(Ex187)Byg/Lrp6Gt(Ex187)Byg
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Absent |
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4B
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| TS17: head |
Present |
Regionally restricted |
4B
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Expression in the orofacial processes in this mutant is the same as in wild-type embryos.
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Specimen
4C:
embryonic day 10.5
(more )
Specimen
4C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
4C
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Expression is in the dorsal neural retina.
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| TS17: head |
Present |
Regionally restricted |
4C
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Expression is in the orofacial processes.
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Specimen
4D:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Lrp6Gt(Ex187)Byg/Lrp6Gt(Ex187)Byg
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Absent |
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4D
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| TS17: head |
Present |
Regionally restricted |
4D
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Expression in the orofacial processes in this mutant is the same as in wild-type embryos.
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Analysis Tools
