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Gene Expression Data
Assay Details
Assay
Reference: J:116645 Cota CD, et al., Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis. Dev Dyn. 2006 Dec;235(12):3438-47
Assay type: RNA in situ
MGI Accession ID: MGI:5553466
Gene symbol: Lefty1
Gene name: left right determination factor 1
Probe: Lefty probe
Probe preparation: Antisense
Assay notes: Data was shown in Table 4. Probe used recognizes both family members.
Results
Specimen +/+ 2-7: embryonic day 8.0 (more )
Note: 2-7 somites.
Structure Level Pattern Image Note
TS12: neural tube floor plate Present Regionally restricted Asymmetrically expressed in the left side.
Specimen md-nc/md-nc 2-7 variant 1: embryonic day 8.0; Mgrn1md-nc/Mgrn1md-nc (more )
Note: 2-7 somites.
Structure Level Pattern Image Note
TS12: neural tube floor plate Present Regionally restricted 66.7% showed asymmetric expression in the left side.
Specimen md-nc/md-nc 2-7 variant 2: embryonic day 8.0; Mgrn1md-nc/Mgrn1md-nc (more )
Note: 2-7 somites.
Structure Level Pattern Image Note
TS12: neural tube floor plate Absent 33.3% showed absent expression.
Specimen md-2J/md-2J 2-7 variant 1: embryonic day 8.0; Mgrn1md-2J/Mgrn1md-2J (more )
Note: 2-7 somites.
Structure Level Pattern Image Note
TS12: neural tube floor plate Present Regionally restricted 83.3% showed asymmetric expression in the left side.
Specimen md-2J/md-2J 2-7 variant 2: embryonic day 8.0; Mgrn1md-2J/Mgrn1md-2J (more )
Note: 2-7 somites.
Structure Level Pattern Image Note
TS12: neural tube floor plate Absent 16.7% showed absent expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory