About   Help   FAQ
Lefty probe Probe Detail
Nucleotide
Probe/Clone
  • Name
    Lefty probe
  • Sequence Type
    cDNA
  • ID
    MGI:1289467
  • Region Covered
    includes a 3' portion of the coding region
  • Parent Clone
  • Vector Type
    Plasmid
  • Insert Site
    Aat1
  • Insert Size
    0.5 kb
Source
  • Species
    mouse, laboratory
  • Tissue
    embryo
  • Cell Line
    embryonal carcinoma cell line P19
Genes
Lefty1 left right determination factor 1
Lefty2 left-right determination factor 2
Expression
  • Assay Results
    113
References
J:32932 Meno C, et al., Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature. 1996 May 9;381(6578):151-5
J:49657 Dufort D, et al., The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. Development. 1998 Aug;125(16):3015-25
J:64329 Welsh IC, et al., Loss of late primitive streak mesoderm and interruption of left-right morphogenesis in the Ednrb(s-1Acrg) mutant mouse. Dev Biol. 2000 Sep 1;225(1):151-68
J:77125 Norris DP, et al., The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development. 2002 Jul;129(14):3455-68
J:116645 Cota CD, et al., Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis. Dev Dyn. 2006 Dec;235(12):3438-47

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory