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Gene Expression Data
Assay Details
Assay
Reference: J:194054 Imuta Y, et al., Generation of knock-in mice that express nuclear enhanced green fluorescent protein and tamoxifen-inducible Cre recombinase in the notochord from Foxa2 and T loci. Genesis. 2013 Mar;51(3):210-8
Assay type: Recombinase reporter
MGI Accession ID: MGI:5552721
Gene symbol: Foxa2
Gene name: forkhead box A2
Reporter: lacZ
Direct Detection
Results
Specimen 3h: embryonic day 7.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E6.5. Embyros were isolated and stained on E7.5.
Structure Level Pattern Image Note
TS11: node Present 3h
TS11: notochordal plate Present 3h
TS11: definitive endoderm Present 3h
Specimen 3i: embryonic day 8.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E6.5. Embyros were isolated and stained on E8.5.
Structure Level Pattern Image Note
TS13: node Present 3i
TS13: notochord Present 3i
TS13: neural tube Present 3i
Specimen 3j: embryonic day 8.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E6.5. Embyros were isolated and stained on E8.5.
Structure Level Pattern Image Note
TS13: notochord Present 3j
TS13: embryo endoderm Present 3j
TS13: embryo Present Scattered 3j Stained cells are observed scattered in some tissues that do not express Foxa2 endogenously.
Specimen 3l: embryonic day 9.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E6.5. Embyros were isolated and stained on E9.5.
Structure Level Pattern Image Note
TS15: notochord Present 3l
TS15: neural tube Present 3l
TS15: embryo endoderm Present 3l
Specimen 3m: embryonic day 9.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E6.5. Embyros were isolated and stained on E9.5.
Structure Level Pattern Image Note
TS15: notochord Present 3m
TS15: neural tube floor plate Present 3m
TS15: foregut Present 3m
Specimen 3n: embryonic day 9.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E6.5. Embyros were isolated and stained on E9.5.
Structure Level Pattern Image Note
TS15: notochord Present 3n
TS15: neural tube floor plate Present 3n
TS15: foregut Present 3n
TS15: hepatic primordium Present 3n Staining is observed in the liver primordium.
TS15: embryo Present Scattered 3n
Specimen 3o: embryonic day 8.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E7.5. Embyros were isolated and stained on E8.5.
Structure Level Pattern Image Note
TS13: neural tube Present 3o Staining pattern is similar with tamoxifen administration at E7.5 to that observed when tamoxifen is administered on E6.5.
TS13: node Present 3o Staining pattern is similar with tamoxifen administration at E7.5 to that observed when tamoxifen is administered on E6.5.
TS13: notochord Present 3o Staining pattern is similar with tamoxifen administration at E7.5 to that observed when tamoxifen is administered on E6.5.
Specimen 3p: embryonic day 9.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E8.5. Embyros were isolated and stained on E9.5.
Structure Level Pattern Image Note
TS15: embryo endoderm Present 3p
TS15: neural tube Present 3p
TS15: notochord Present 3p
Specimen 3q: embryonic day 9.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E8.5. Embyros were isolated and stained on E9.5.
Structure Level Pattern Image Note
TS15: notochord Present 3q
TS15: foregut Present 3q
TS15: neural tube floor plate Present 3q
TS15: embryo Present Scattered 3q Stained cells are observed scattered in some tissues that do not express Foxa2 endogenously.
Specimen 3r: embryonic day 9.5; Foxa2tm1(cre/ERT2)Hssk/Foxa2+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Tamoxifen (0.12 mg/g BW) was administered by gavage on E8.5. Embyros were isolated and stained on E9.5.
Structure Level Pattern Image Note
TS15: notochord Present 3r
TS15: foregut Present 3r
TS15: neural tube floor plate Present 3r
TS15: hepatic primordium Present 3r
TS15: embryo Present Scattered 3r Stained cells are observed scattered in some tissues that do not express Foxa2 endogenously.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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