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Gene Expression Data
Assay Details
Assay
Reference: J:117226 Wei K, et al., Myocardin-related transcription factor B is required for normal mouse vascular development and smooth muscle gene expression. Dev Dyn. 2007 Feb;236(2):416-25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5551849
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: anti-smooth muscle alpha actin
Detection system: Secondary antibody
Results
Specimen 4A: embryonic day 16.5; MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg (more )
Structure Level Pattern Image Note
TS24: heart Present 4A Ths mutant has heart defects.

Specimen 4B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: heart Present 4B

Specimen 5E: embryonic day 15.5; MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg (more )
Structure Level Pattern Image Note
TS23: umbilical artery Weak Regionally restricted 5E
TS23: umbilical vein Weak Regionally restricted 5E

Specimen 5F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: umbilical artery Present Regionally restricted 5F Expression is in the vitelline artery and vein.
TS23: umbilical vein Present Regionally restricted 5F Expression is in the vitelline artery and vein.

Specimen 5G: embryonic day 15.5; MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg (more )
Structure Level Pattern Image Note
TS23: yolk sac Weak 5G

Specimen 5H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: yolk sac Present 5H

Specimen 7A: embryonic day 15.5; MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg (more )
Structure Level Pattern Image Note
TS23: blood vessel Weak Regionally restricted 7A Expression is in central veins and in the liver parenchyma surrounding sinusoids.
TS23: liver Weak Regionally restricted 7A Expression is in central veins and in the liver parenchyma surrounding sinusoids.

Specimen 7B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: blood vessel Present Regionally restricted 7B Expression is in central veins and in the liver parenchyma surrounding sinusoids.
TS23: liver Present Regionally restricted 7B Expression is in central veins and in the liver parenchyma surrounding sinusoids.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory