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Gene Expression Data
Assay Details
Assay
Reference: J:108819 Miyoshi T, et al., Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants. Dev Dyn. 2006 Apr 5;235(7):1941-1952
Assay type: RNA in situ
MGI Accession ID: MGI:5550484
Gene symbol: Zeb2
Gene name: zinc finger E-box binding homeobox 2
Probe: Sip1 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2Aa: embryonic day 7.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 2Aa
Specimen 2Ac: embryonic day 7.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS11: primitive endoderm Present Regionally restricted 2Ac Expressed more strongly in the primitive endoderm in the posterior part of the embryo.
Specimen 2Ba: embryonic day 8.0; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: embryo ectoderm Present Widespread 2Ba
TS12: embryo endoderm Present Widespread 2Ba
TS12: embryo mesenchyme Present Widespread 2Ba
TS12: neural fold Strong Regionally restricted 2Ba Strongest expression in the anterior neural fold.
TS12: paraxial mesenchyme Present 2Ba
Specimen 2Bc: embryonic day 8.0; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: node Absent 2Bc
TS12: notochordal plate Absent 2Bc Absent in the prechordal plate anteriorly extending from the node.
TS12: neural fold Strong Regionally restricted 2Bc Strongest expression in the anterior neural fold.
TS12: paraxial mesenchyme Present 2Bc
Specimen 2Be: embryonic day 8.0; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Present 2Be
Specimen 2Bg: embryonic day 8.0; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: primitive streak Present 2Bg
Specimen 2Ca left: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 2Ca left Expressed throughout the neural plate/tube, with markedly decreased expression in the anterior margin and rhombomeres 3 and 5.
TS13: anterior pro-rhombomere neural fold Weak Regionally restricted 2Ca left Low expression in the anterior margin.
TS13: rhombomere 3 Weak 2Ca left
TS13: rhombomere 5 Weak 2Ca left
Specimen 2Ca right: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 2Ca right Expressed throughout the neural plate/tube, with markedly decreased expression in the anterior margin and rhombomeres 3 and 5.
TS13: rhombomere 3 Weak 2Ca right
TS13: rhombomere 5 Weak 2Ca right
Specimen 2Ca inset: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite. Double labeled: blue - Zeb2; red - Egr2 (Krox20; assay MGI:5550542).
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 2Ca inset Expressed throughout the neural plate/tube, with markedly decreased expression in the anterior margin and rhombomeres 3 and 5.
TS13: rhombomere 3 Weak 2Ca inset
TS13: rhombomere 5 Weak 2Ca inset
Specimen 2Cc: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: future midbrain Present 2Cc
TS13: future prosencephalon Present 2Cc
Specimen 2Ce: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: embryo endoderm Absent 2Ce
TS13: node Absent 2Ce
TS13: notochord Absent 2Ce
TS13: neural tube Present 2Ce
TS13: somite Present 2Ce
Specimen 2Cg: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present 2Cg
TS13: node Absent 2Cg
Specimen 3Aa: embryonic day 9.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 3Aa
TS15: neural tube Present 3Aa
TS15: trigeminal preganglion Present 3Aa
Specimen 3Ba: embryonic day 10.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 3Ba
TS17: trigeminal ganglion Present 3Ba
Specimen 3Bc: embryonic day 10.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 3Bc
Specimen 3Ca: embryonic day 11.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS19: embryo Present 3Ca
Specimen 3Cc: embryonic day 11.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS19: maxilla primordium Strong Regionally restricted 3Cc Expressed in the lateral part.
TS19: nasal pit Absent 3Cc
Specimen 3Ce: embryonic day 11.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 3Ce Expressed in the corpus striatum.
TS19: trigeminal ganglion Present 3Ce
TS19: neural tube ventricular layer Present Regionally restricted 3Ce Expressed in the ventricular zone where neuroepithelial stem cells reside.
Specimen 3Cg: embryonic day 11.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 3Cg
TS19: neural tube ventricular layer Strong Regionally restricted 3Cg Expressed in the ventricular zone where neuroepithelial stem cells reside.
Specimen not shown: embryonic day 8.5; Zeb1tm2Yhi/Zeb1tm2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: embryo Present Same as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory