Gene Expression Data
Assay Details
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Assay
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Reference:
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J:111612
Uemura M, et al., alphaN-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Dev Dyn. 2006 May 11;235(9):2559-2566
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5547983
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Gene symbol:
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Nefm
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Gene name:
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neurofilament, medium polypeptide
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Results
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Specimen
2A:
embryonic day 11.5
(more  )
Specimen
2A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2B:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2C:
postnatal day 0
(more )
Specimen
2C:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2D:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: anterior commissure |
Present |
Regionally restricted |
2D
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Expression is present, but this mutant is missing the anterior commissure in the vicinity of the midline.
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| TS27: forebrain |
Present |
Regionally restricted |
2D
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Expression is present but the mammillothalamic tract is thinner in this mutant.
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| TS27: fornix |
Present |
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2D
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Expression is present, but the fornix is dispersed.
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| TS27: hypoglossal nucleus |
Present |
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2D
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Expression is present but the nucleus is atrophied.
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Specimen
2E:
postnatal day 0
(more )
Specimen
2E:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2F:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: anterior commissure |
Present |
Regionally restricted |
2F
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Expression is present, but this mutant is missing the anterior commissure in the vicinity of the midline.
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| TS27: forebrain |
Present |
Regionally restricted |
2F
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Expression is present but the mammillothalamic tract is thinner in this mutant.
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| TS27: fornix |
Present |
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2F
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Expression is present, but the fornix is dispersed.
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| TS27: hypoglossal nucleus |
Present |
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2F
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Expression is present, but the nucleus is atrophied.
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Specimen
3A:
postnatal day 0
(more )
Specimen
3A:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3B:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: anterior commissure |
Present |
Regionally restricted |
3B
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The anterior part of the anterior commissure is disrupted around the midline region.
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Specimen
3C:
postnatal day 0
(more )
Specimen
3C:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3D:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: anterior commissure |
Present |
Regionally restricted |
3D
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The anterior part of the anterior commissure is disrupted around the midline region.
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Specimen
3E:
postnatal day 0
(more )
Specimen
3E:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3F:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: anterior commissure |
Present |
Regionally restricted |
3F
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The stria terminalis is disrupted around the midline region.
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Specimen
3R,T:
embryonic day 15.5
(more )
Note: Double labeled: green - Nefm; red - Ctnna2 (assay MGI:5547982).
Specimen
3R,T:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Nefm; red - Ctnna2 (assay MGI:5547982).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: diencephalon |
Present |
Regionally restricted |
3R
,
3T
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Expression is in the anterior commissure.
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Specimen
3U,W:
embryonic day 15.5
(more )
Note: Double labeled: green - Nefm; red - Ctnna2 (assay MGI:5547982).
Specimen
3U,W:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Nefm; red - Ctnna2 (assay MGI:5547982).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: diencephalon |
Present |
Regionally restricted |
3U
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3V
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Expression is in the anterior commissure.
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Specimen
5G:
postnatal day 0
(more )
Note: Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
Specimen
5G:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
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Specimen
5H:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
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Specimen
5K:
embryonic day 14.5
(more )
Note: Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
Specimen
5K:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
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Specimen
5L:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
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Specimen
5O:
embryonic day 14.5
(more )
Specimen
5O:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: nerve |
Present |
Regionally restricted |
5O
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Staining illustrates innervations of the tongue.
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| TS22: tongue |
Present |
Regionally restricted |
5O
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Staining illustrates innervations of the tongue.
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Specimen
5P:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: nerve |
Weak |
Regionally restricted |
5P
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Staining illustrates that innervation of the tongue is reduced in this mutant.
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| TS22: tongue |
Weak |
Regionally restricted |
5P
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Staining illustrates that innervation of the tongue is reduced in this mutant.
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Specimen
6J:
postnatal day 0
(more )
Note: Double labeled: red - Nefm; green - Calb1 (assay MGI:5548087).
Specimen
6J:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Nefm; green - Calb1 (assay MGI:5548087).
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Specimen
6K:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Nefm; green - Calb1 (assay MGI:5548087).
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