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Gene Expression Data
Assay Details
Assay
Reference: J:111612 Uemura M, et al., alphaN-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Dev Dyn. 2006 May 11;235(9):2559-2566
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5548087
Gene symbol: Calb1
Gene name: calbindin 1
Antibody: anti-calbindin
Detection system: Secondary antibody
Results
Specimen 3P: embryonic day 17.5 (more )
Note: Double labeled: blue - Calb1; red - Ctnna2 (assay MGI:5547982).
Structure Level Pattern Image Note
TS25: anterior commissure Present 3P
Specimen 5A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindbrain Present 5A Expression is in the hypoglossal nucleus. Expression is in the hypoglossal nucleus.
Specimen 5D: embryonic day 14.5 (more )
Note: Double labeled: green - Calb1; red - Ctnna2 (assay MGI:5547982).
Structure Level Pattern Image Note
TS22: hindbrain Present Regionally restricted 5D Expression is in the hypoglossal nucleus.
Specimen 5G: postnatal day 0 (more )
Note: Double labeled: red - Calb1; green - Nefm (assay MGI:5547983).
Structure Level Pattern Image Note
TS27: hypoglossal nucleus Present 5G
Specimen 5H: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Note: Double labeled: red - Calb1; green - Nefm (assay MGI:5547983).
Structure Level Pattern Image Note
TS27: hypoglossal nucleus Absent 5H
Specimen 5K: embryonic day 14.5 (more )
Note: Double labeled: red - Calb1; green - Nefm (assay MGI:5547983).
Structure Level Pattern Image Note
TS22: hindbrain Present Regionally restricted 5K Expression is in the hypoglossal nucleus.
Specimen 5L: embryonic day 14.5; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Note: Double labeled: red - Calb1; green - Nefm (assay MGI:5547983).
Structure Level Pattern Image Note
TS22: hindbrain Weak Regionally restricted 5L Expression is in the hypoglossal nucleus and many neurons are missing in this mutant.
Specimen 5M: embryonic day 14.5 (more )
Note: Triple labeled: green - Calb1; red - Nes (RC2; assay MGI:5550089); blue - L1cam (assay MGI:5550090).
Structure Level Pattern Image Note
TS22: hindbrain Present Regionally restricted 5M Expression is in the hypoglossal nucleus.
Specimen 5N: embryonic day 14.5; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Note: Triple labeled: green - Calb1; red - Nes (RC2; assay MGI:5550089); blue - L1cam (assay MGI:5550090).
Structure Level Pattern Image Note
TS22: hindbrain Weak Regionally restricted 5N Expression is in the hypoglossal nucleus and many neurons are missing in this mutant.
Specimen 6J: postnatal day 0 (more )
Note: Double labeled: green - Calb1; red - Nefm (assay MGI:5547983).
Structure Level Pattern Image Note
TS27: mammillary body Present 6J
Specimen 6K: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Note: Double labeled: green - Calb1; red - Nefm (assay MGI:5547983).
Structure Level Pattern Image Note
TS27: mammillary body Present 6K Expression is present and shows that axons from the principal mammillary tract are not fully fasciculated in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory