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Gene Expression Data
Assay Details
Assay
Reference: J:93808 Chuva de Sousa Lopes SM, et al., Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn. 2004 Nov;231(3):542-50
Assay type: RNA in situ
MGI Accession ID: MGI:5528275
Gene symbol: Ccn2
Gene name: cellular communication network factor 2
Probe: hCtgf cDNA
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: parietal endoderm Strong 1A
TS28: decidua Strong 1A
Specimen 1B: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: parietal endoderm Strong 1B
TS28: decidua Strong 1B
Specimen 1C: embryonic day 8.0-8.5 (more )
Structure Level Pattern Image Note
TS13: 1st branchial pouch Present 1C
TS13: foregut diverticulum Present 1C
TS13: head mesenchyme Present 1C
TS13: notochord Present 1C
TS13: neural tube floor plate Weak 1C
TS13: neural tube roof plate Weak 1C
Specimen 1D: embryonic day 8.0-8.5 (more )
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Strong 1D
TS13: heart Present 1D Strong expression in the myocardium, absent in the endocardium.
Specimen 1E: embryonic day 8.5-9.0 (more )
Structure Level Pattern Image Note
TS14: cardiac muscle tissue Strong Patchy 1E
Specimen 1F: embryonic day 8.5-9.0 (more )
Structure Level Pattern Image Note
TS14: cardiac muscle tissue Strong Patchy 1F
Specimen 1G: embryonic day 9.5-10.5 (more )
Structure Level Pattern Image Note
TS16: heart Present Patchy 1G
TS16: nervous system Present Regionally restricted 1G
TS16: branchial arch artery Present 1G
TS16: common cardinal vein Present 1G
TS16: dorsal aorta Present 1G
TS16: foregut Present 1G
TS16: head mesenchyme Present 1G
TS16: notochord Present 1G
Specimen 1H: embryonic day 9.5-10.5 (more )
Structure Level Pattern Image Note
TS16: heart Present Regionally restricted 1H
TS16: nervous system Present Regionally restricted 1H
TS16: 1st branchial arch Present Regionally restricted 1H Expression is in the outer-lateral parts.
TS16: 2nd branchial arch Present Regionally restricted 1H Expression is in the outer-lateral parts.
TS16: branchial arch artery Present 1H
TS16: head mesenchyme Present 1H
Specimen 1I: embryonic day 9.5-10.5 (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch Present Regionally restricted 1I Expression is in the outer-lateral parts.
TS16: 2nd branchial arch Present Regionally restricted 1I Expression is in the outer-lateral parts.
TS16: nervous system Present Regionally restricted 1I
TS16: branchial arch artery Present 1I
TS16: foregut Present 1I
TS16: head mesenchyme Present 1I
Specimen 2C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present Patchy 2C
Specimen 2D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present Patchy 2D
Specimen 2E: embryonic day 9.5; Bmp4tm1Blh/Bmp4tm1Blh (more )
Structure Level Pattern Image Note
TS15: common atrial chamber cardiac muscle Strong 2E This embryo did not undergo "turning".
Specimen 2F: embryonic day 9.5; Bmp4tm1Blh/Bmp4tm1Blh (more )
Structure Level Pattern Image Note
TS15: common atrial chamber cardiac muscle Strong 2F This embryo did not undergo "turning".
Specimen 2G: embryonic day 9.5; Bmp4tm1Blh/Bmp4tm1Blh (more )
Structure Level Pattern Image Note
TS15: bulbus cordis Strong 2G
TS15: heart Strong Regionally restricted 2G Expression is in the aortic sac.
Specimen 2H: embryonic day 9.5; Bmp4tm1Blh/Bmp4tm1Blh (more )
Structure Level Pattern Image Note
TS15: bulbus cordis Strong 2H
TS15: heart Strong Regionally restricted 2H Expression is in the aortic sac.
Specimen 2I: embryonic day 9.5; Tgfbr1tm1Karl/Tgfbr1tm1Karl (more )
Structure Level Pattern Image Note
TS15: common atrial chamber cardiac muscle Strong 2I This embryo did not undergo "turning".
Specimen 2J: embryonic day 9.5; Tgfbr1tm1Karl/Tgfbr1tm1Karl (more )
Structure Level Pattern Image Note
TS15: common atrial chamber cardiac muscle Strong 2J This embryo did not undergo "turning".
Specimen 2K: embryonic day 9.5; Tgfbr1tm1Karl/Tgfbr1tm1Karl (more )
Structure Level Pattern Image Note
TS15: bulbus cordis Strong 2K
TS15: heart Strong Regionally restricted 2K Expression is in the aortic sac.
Specimen 2L: embryonic day 9.5; Tgfbr1tm1Karl/Tgfbr1tm1Karl (more )
Structure Level Pattern Image Note
TS15: bulbus cordis Strong 2L
TS15: heart Strong Regionally restricted 2L Expression is in the aortic sac.
Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart Strong 3A Expression is in the myocardial trabeculation.
TS20: endocardial cushion Strong 3A
TS20: heart ventricle Strong Regionally restricted 3A Expression is in the nontrabeculated region of the ventricles underneath the leaflets.
TS20: dorsal aorta Present 3A
TS20: pulmonary artery Present 3A
TS20: blood vessel Present Regionally restricted 3A Expression is in all large blood vessels.
Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart Strong 3B Expression is in the myocardial trabeculation.
TS20: endocardial cushion Strong 3B
TS20: dorsal aorta Present 3B
TS20: pulmonary artery Present 3B
TS20: blood vessel Present Regionally restricted 3B Expression is in all large blood vessels.
Specimen 3C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart Strong 3C Expression is in the myocardial trabeculation.
TS22: endocardial cushion Strong 3C
TS22: heart ventricle Strong Regionally restricted 3C Expression is in the nontrabeculated region of the ventricles underneath the leaflets.
TS22: dorsal aorta Present 3C
TS22: ductus arteriosus Present 3C
TS22: pulmonary artery Present 3C
TS22: pulmonary trunk Present 3C
TS22: blood vessel Present Regionally restricted 3C Expression is in all large blood vessels.
TS22: aortic valve Weak Regionally restricted 3C Low or no expression.
TS22: pulmonary valve Weak Regionally restricted 3C Low or no expression.
Specimen 3D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart Strong 3D Expression is in the myocardial trabeculation.
TS22: endocardial cushion Strong 3D
TS22: dorsal aorta Present 3D
TS22: ductus arteriosus Present 3D
TS22: pulmonary artery Present 3D
TS22: pulmonary trunk Present 3D
TS22: blood vessel Present Regionally restricted 3D Expression is in all large blood vessels.
TS22: aortic valve Weak Low or no expression.
TS22: pulmonary valve Weak Low or no expression.
Specimen 3E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: heart Present Ubiquitous 3E Patchy ubiquitous expression.
Specimen 3F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: heart atrium Present 3F
TS28: heart ventricle Present Regionally restricted 3F Absent myocytes and fibroblasts, present in the large blood vessels of the ventricles.
Specimen 4C inset: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: aortic valve Present 4C inset
TS24: pulmonary valve Present 4C inset
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory