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Gene Expression Data
Assay Details
Assay
Reference: J:58233 Eisenstat DD, et al., DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation. J Comp Neurol. 1999 Nov 15;414(2):217-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5523862
Gene symbol: Dlx5
Gene name: distal-less homeobox 5
Antibody: DLX-5/N117 antibody
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2F: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon Present 2F Expression is in the subcortical telencephalon, itincludes the large ganglionic eminence, the medial ganglionic eminence, the preoptic area, the anterior entopeduncular area, and parts of the septal and amygdalar primordia.
TS18: diencephalon Present Regionally restricted 2F Expression is in the rostral diencephalon and hypothalamus just anterior of the zona limitans intrathalamica, extending through the ventral thalamus, the supraoptoparaventricular area, the hypothalamic cell cord, and ending in the suprachiasmatic area.
TS18: diencephalon lateral wall ventricular layer Present Regionally restricted 2F
TS18: telencephalon ventricular layer Present Regionally restricted 2F
TS18: diencephalon lateral wall mantle layer Strong Regionally restricted 2F
TS18: telencephalon mantle layer Strong Regionally restricted 2F

Specimen 2L: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon ventricular layer Present 2L
TS18: telencephalon mantle layer Strong 2L

Specimen 2R: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon ventricular layer Present 2R
TS18: telencephalon mantle layer Strong 2R

Specimen 3I,M,Q: embryonic day 11.0 (more )
Note: M and Q are higher magnifications of the boxed area in I.
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3I , 3M , 3Q Expression is in the rostral diencephalon and hypothalamus just anterior of the zona limitans intrathalamica, extending through the ventral thalamus, the supraoptoparaventricular area, the hypothalamic cell cord, and ending in the suprachiasmatic area.

Specimen 3L: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3L Expression is in the supraoptoparaventricular area and ventral thalamus with a caudal limit at the zona limitans intrathalamica.

Specimen 3T: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3T Expression is in the hypothalamus.

Specimen 4F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ganglionic eminence Present 4F

Specimen 4L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 4L Expression is in the nucleus forming in prosomere 3 and in periventricular cell populations that may contribute to the zona incerta and to the paraventricular nucleus.

Specimen 5F: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx5; blue/purple - Dlx2 (assay MGI:5523240).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5F Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen 5G: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx5; blue/purple - Dlx2 (assay MGI:5523240).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5G Expression is in the medial ganglionic eminence (shown is the subventricular zone).

Specimen 5M: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx5; blue/purple - Dlx1 (assay MGI:5523863).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5M Expression is in the medial ganglionic eminence.

Specimen 5N: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx5; blue/purple - Dlx1 (assay MGI:5523863).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5N Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen 5T: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx5; blue/purple - Dlx5 (assay MGI:5523864).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5T Expression is in the medial ganglionic eminence.

Specimen 5U: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx5; blue/purple - Dlx5 (assay MGI:5523864).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5U Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen not shown E10,5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: eye Absent

Specimen not shown E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: retina Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory