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Gene Expression Data
Assay Details
Assay
Reference: J:77820 Kameda Y, et al., Homeobox gene hoxa3 is essential for the formation of the carotid body in the mouse embryos. Dev Biol. 2002 Jul 1;247(1):197-209
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5506935
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 3rd arch artery Present Regionally restricted 6A Expressed in the wall.
TS17: dorsal aorta Present Regionally restricted 6A Expressed in the wall.
Specimen 6B: embryonic day 10.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS17: 3rd arch artery Present Regionally restricted 6B Expressed in the wall.
TS17: 4th arch artery Present 6B More intense staining and larger diameter than that of wild types.
TS17: dorsal aorta Present 6B
Specimen 6C: embryonic day 10.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS17: 3rd arch artery Present Regionally restricted 6C Expressed in the wall, particularly at the ventral part.
TS17: 4th arch artery Present 6C More intense staining and larger diameter than that of wild types.
TS17: dorsal aorta Present 6C
Specimen 6D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: 3rd arch artery Present 6D
TS19: 4th arch artery Present 6D
TS19: dorsal aorta Present 6D
Specimen 6E: embryonic day 11.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS19: dorsal aorta Present 6E
TS19: 4th arch artery Present 6E
TS19: 6th arch artery Present 6E
Specimen 6F: embryonic day 11.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS19: 3rd arch artery Trace 6F The degenerating artery almost disappeared with little expression.
TS19: 4th arch artery Present 6F More developed. More accumulations around the fourth and sixth arch arteries near the aortic sac.
TS19: 6th arch artery Present 6F More developed. More accumulations around the fourth and sixth arch arteries near the aortic sac.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory