Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:68672
Zhao J, et al., Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis. Dev Biol. 2001 Apr 1;232(1):204-18
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:5505801
|
|
Gene symbol:
|
Sftpc
|
|
Gene name:
|
surfactant associated protein C
|
|
Antibody:
|
anti-SP-C
|
|
Detection system:
|
Secondary antibody
|
|
|
Results
|
Specimen
4C:
embryonic day 16.5
(more )
Specimen
4C:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 16.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: lung epithelium |
Present |
Regionally restricted |
4C
|
Expression is in the distal epithelial branches.
|
Specimen
4D:
(close )
|
Genetic Background:
|
involves: 129 * DBA/1J
|
|
Mutant Allele(s):
|
Adam17tm1Imx/Adam17tm1Imx
|
|
Age:
|
embryonic day 16.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: lung epithelium |
Weak |
Patchy |
4D
|
Mutant lungs have fewer staining-positive distal epithelial branches than wild-type.
|
|