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Gene Expression Data
Assay Details
Assay
Reference: J:82633 Adamska M, et al., Doubleridge, a mouse mutant with defective compaction of the apical ectodermal ridge and normal dorsal-ventral patterning of the limb. Dev Biol. 2003 Mar 15;255(2):350-62
Assay type: RNA in situ
MGI Accession ID: MGI:5499813
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA13
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A/C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud ectoderm Present Regionally restricted 4A , 4C Expression was detected in the entire ventral forelimb ectoderm.
Specimen 4E/G: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: forelimb bud ectoderm Present Regionally restricted 4E , 4G Expression was restricted to less than half of the proximal forelimb ectoderm.
Specimen 4I/K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 4K , 4I
Specimen 4O: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 4O
Specimen 6A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 6A
Specimen 7A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 7A
Specimen 7E: embryonic day 11.5 (more )
Note: Double labeled: red - Fgf8; blue - Wnt7a (assay MGI:5499815).
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 7E
Specimen 8B: embryonic day 11.5 (more )
Note: Double labeled: pink - Fgf8; purple - Shh (assay MGI:5499820).
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 8B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory