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Gene Expression Data
Assay Details
Assay
Reference: J:76263 Stricker S, et al., Role of Runx genes in chondrocyte differentiation. Dev Biol. 2002 May 1;245(1):95-108
Assay type: RNA in situ
MGI Accession ID: MGI:5498681
Gene symbol: Runx3
Gene name: runt related transcription factor 3
Probe: Runx3 probe1
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 1C 11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 1C left

Specimen 1C 12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present 1C right

Specimen 1D: embryonic day 14.5; Runx2tm1Mjo/Runx2tm1Mjo (more )
Structure Level Pattern Image Note
TS22: limb Strong 1D Normal expression.

Specimen 2A 13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: metacarpus pre-cartilage condensation Strong Regionally restricted 2A lower left Strong expression in the perichondrium and to a lesser degree within chondrocytes of the metacarpal anlagen.
TS21: forelimb phalanx pre-cartilage condensation Strong Regionally restricted 2A lower left Strong expression in the perichondrium and to a lesser degree within chondrocytes of the proximal phalanges, and in a region corresponding to the future distal phalanges/claws.
TS21: carpus pre-cartilage condensation Absent 2A lower left
TS21: hand joint Absent 2A lower left

Specimen 2B 14.5 upper left: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present Regionally restricted 2B 14.5 runx3 upper left Expressed in prehypertrohic chondrocytes and to a lesser degree in the perichondrium.

Specimen 2B 15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted 2B 15.5 runx3 Expressed in prehypertrohic chondrocytes and the perichondrium. Weak expression in the bone marrow cavity. No expression in hypertrophic chondrocytes.

Specimen 2B 14.5 bottom right: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: elbow joint primordium Absent 2B 14.5 runx3 bottom right No expression in cartilage or perichondrium around the future elbow joint.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: limb digit Present Regionally restricted Expressed in the perichondrium and the chondrocytes located in the proximal part of the metacarpals and phalanges.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory