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Gene Expression Data
Assay Details
Assay
Reference: J:95017 Parlato R, et al., An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev Biol. 2004 Dec 15;276(2):464-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5495841
Gene symbol: Pax8
Gene name: paired box 8
Antibody: anti-Pax8
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1E: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 1E

Specimen 1F: embryonic day 9.0; Hhextm1Rbe/Hhextm1Rbe (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 1F Expression is comparable to the wild type.

Specimen 1G: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 1G

Specimen 1H: embryonic day 10.0; Hhextm1Rbe/Hhextm1Rbe (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present Regionally restricted 1H Strong reduction in expression level, compared with those of the wild type. Only a few non-migrating cells can still be detected.

Specimen 2A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 2A

Specimen 2B: embryonic day 9.0; Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 2B Expression is comparable to those of the wild-type bud.

Specimen 2C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 2C

Specimen 2D: embryonic day 10.0; Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 2D Slightly reduced expression.

Specimen 7F: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 7F

Specimen 7I: embryonic day 10.0; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 7I


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory