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Gene Expression Data
Assay Details
Assay
Reference: J:180120 Chauhan BK, et al., Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18289-94
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5485419
Gene symbol: Myh10
Gene name: myosin, heavy polypeptide 10, non-muscle
Antibody: anti-myosin IIB
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3C left: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Present 3C left Expressed at both the apex and the base of the epithelial cells.
Specimen 3C middle: embryonic day 10.5; Rhoatm1Yuyo/Rhoatm1Yuyo, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: lens pit Present 3C middle Reduced expression both the apex and the base.
Specimen 3C right: embryonic day 10.5; Rac1tm1Djk/Rac1tm1Djk, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: lens pit Present 3C right Similar to the control, but shows a slightly higher, broader peak at the apex and a slightly lower peak at the base.
Specimen S1 A/B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Present S1_B myosin IIB , S1_A , S1_B merge Expressed at the base of the epithelial cells.
Specimen S1 E/F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Present S1_F , S1_E Expressed at the apex and the base of epithelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory