Otop1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171566 Kim E, et al., Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. J Neurophysiol. 2010 Dec;104(6):3439-50
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5476800
Gene symbol:	Otop1
Gene name:	otopetrin 1

Antibody:	OTOP1 antibody
Detection system:	Secondary antibody

Results

Specimen 3A,C: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: saccule	Present	Regionally restricted	3A , 3C	Expression is near the apical surface in supporting cells in the extrastriolar regions of the sensory epithelium.
TS24: utricle	Present	Regionally restricted	3A , 3C	Expression is near the apical surface in supporting cells in the extrastriolar regions of the sensory epithelium.

Specimen 3D,F: embryonic day 16.5; Otop1^tm1Dor/Otop1^tm1Dor (more

)
Note: Double labeled: red - Otop1 protein; green - Otop1 reporter (assay MGI:5476788).

Structure	Level	Pattern	Image	Note
TS24: saccule	Present	Regionally restricted	3F , 3D	Expression is near the apical surface in supporting cells in the extrastriolar regions of the sensory epithelium.
TS24: utricle	Present	Regionally restricted	3F , 3D	Expression is near the apical surface in supporting cells in the extrastriolar regions of the sensory epithelium.

Specimen 4A-C: embryonic day 16.5 (more

)
Note: Double labeled: red - Otop1; green - Tjp1 (ZO-1; assay MGI:5478583).

Structure	Level	Pattern	Image	Note
TS24: utricle	Present	Regionally restricted	4C , 4B , 4A	Expression is near the apical surface in supporting cells in the extrastriolar regions of the sensory epithelium.

Specimen 4D,E: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: macula of utricle	Present		4D , 4E

Specimen 4F: postnatal day 0; Otop1^tm1Dor/Otop1^tm1Dor (more

)
Note: Double labeled: green - Otop1; red - Pvalb (assay MGI:5478585).

Structure	Level	Pattern	Image	Note
TS27: macula of utricle	Present		4F

Specimen S1 A: postnatal (more

)

Structure	Level	Pattern	Image	Note
TS28: macula of utricle	Present	Regionally restricted	S1A	Expression is near the apical surface in supporting cells in the extrastriolar regions of the sensory epithelium.

Specimen S1 B: postnatal; Otop1^tm1Dor/Otop1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: macula of utricle	Present	Punctate	S1B

Specimen S1 C: postnatal; Otop1^tm1Dor/Otop1^tm1Dor (more

)

Structure	Level	Pattern	Image	Note
TS28: macula of utricle	Strong	Punctate	S1C

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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