Otop1^tm1Dor
Targeted Allele Detail

Summary

• Symbol: Otop1^tm1Dor
• Name: otopetrin 1; targeted mutation 1, David M Ornitz
• MGI ID: MGI:4950042
• Synonyms: Otop1^betagal
• Gene: Otop1 Location: Chr5:38434748-38461560 bp, + strand Genetic Position: Chr5, 20.35 cM
• Alliance: Otop1^tm1Dor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171566
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The last 62 bp of exon 2 and 2.7 kb of intron 2 were replaced with beta-gal gene and a floxed neo cassette. (J:171566)

Expression

In Mice Carrying this Mutation:	33 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Otop1 Mutation: 38 strains or lines available

References

• Original: J:171566 Kim E, et al., Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. J Neurophysiol. 2010 Dec;104(6):3439-50
• All: 2 reference(s)