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Gene Expression Data
Assay Details
Assay
Reference: J:171566 Kim E, et al., Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. J Neurophysiol. 2010 Dec;104(6):3439-50
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5476788
Gene symbol: Otop1
Gene name: otopetrin 1
Reporter: lacZ
Direct Detection
Assay notes: Fixative was 0.2% glutaraldehyde.
Results
Specimen 2A, B: embryonic day 13.5; Otop1tm1Dor/Otop1tm1Dor (more )
Note: (B,D,F) Higher magnifications of (A,B,C).
Structure Level Pattern Image Note
TS21: utricle Present 2A , 2B
TS21: cochlea Absent 2A , 2B
TS21: saccule Absent 2A , 2B

Specimen 2C, D: embryonic day 14.5; Otop1tm1Dor/Otop1tm1Dor (more )
Note: (B,D,F) Higher magnifications of (A,B,C).
Structure Level Pattern Image Note
TS22: saccule Present 2C , 2D
TS22: utricle Present 2C , 2D
TS22: cochlea Absent 2C , 2D

Specimen 2E, F: embryonic day 16.5; Otop1tm1Dor/Otop1tm1Dor (more )
Note: (B,D,F) Higher magnifications of (A,B,C).
Structure Level Pattern Image Note
TS24: saccule Present 2E , 2F
TS24: utricle Present 2E , 2F
TS24: cochlea Absent 2F , 2E

Specimen 2G: postnatal day 0; Otop1tm1Dor/Otop1tm1Dor (more )
Note: (I) High magnification of the boxed area in (G).
Structure Level Pattern Image Note
TS27: macula of utricle Present Regionally restricted 2G , 2I Expression is in the sensory epithelium and is absent in the striola region.

Specimen 2H: postnatal day 0; Otop1tm1Dor/Otop1tm1Dor (more )
Structure Level Pattern Image Note
TS27: macula of saccule Present Regionally restricted 2H Expression is in the sensory epithelium and is absent in the striola region.

Specimen 2J: postnatal day 0; Otop1tm1Dor/Otop1tm1Dor (more )
Structure Level Pattern Image Note
TS27: macula of utricle Present Regionally restricted 2J Expression is in the sensory and transitionary epithelium.

Specimen 2K: postnatal day 12; Otop1tm1Dor/Otop1tm1Dor (more )
Structure Level Pattern Image Note
TS28: macula of utricle Present Regionally restricted 2K Expression is in the sensory and transitionary epithelium, absent in striola region.

Specimen 2L: postnatal month 6; Otop1tm1Dor/Otop1tm1Dor (more )
Structure Level Pattern Image Note
TS28: macula of utricle Present Regionally restricted 2L Expression is in the sensory and transitionary epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory