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Gene Expression Data
Assay Details
Assay
Reference: J:29671 Bitgood MJ, et al., Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol. 1995 Nov;172(1):126-38
Assay type: RNA in situ
MGI Accession ID: MGI:5468144
Gene symbol: Bmp2
Gene name: bone morphogenetic protein 2
Probe: BMP2 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted 1B Expression is concentrated in the central region of the tooth germ (epithelial thickening).
Specimen 1E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted 1E As the epithelial placode involutes into the underlying jaw mesenchyme, expression continues to be in mesial epithelial cells.
Specimen 1H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel knot Present 1H
TS22: dental papilla Present Regionally restricted 1H Expressed in the deepest portion.
Specimen 1K: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dental papilla Present Regionally restricted 1K Expressed in the deepest portion.
Specimen 1N: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dental papilla Strong Regionally restricted 1N Expressed in the odontoblasts.
Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vibrissa epidermal component Present 2B Expressed in the epithelial whisker placode.
Specimen 2E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vibrissa epidermal component Present Regionally restricted 2E Expressed in basal matrix cells.
Specimen 2H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa follicle Present Regionally restricted 2H Expressed in the precortical cells.
Specimen 5O: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: duodenum Present Regionally restricted 5O Expressed at tips of the villi.
Specimen 5R: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: rectum epithelium Present Regionally restricted 5R Expressed in a subset cells closest to the lumen.
Specimen 6G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: atrioventricular canal Present Regionally restricted 6G Expressed in myocardium underlying the atrioventricular valve.
TS20: outflow tract Present Regionally restricted 6G Expressed in myocardium underlying the truncus arteriosus.
Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: urethra Present Regionally restricted Expressed in a thin sheet of epithelium lumenal to the thick epithelial lining that expresses Shh, and a subset of the Bmp4 expressing mesenchyme that is located immediately adjacent to the Shh-expressing cells.
Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hard palate palatal rugae Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory