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BMP2 cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    BMP2 cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:11030
  • Region Covered
    includes coding region and 3' untranslated
  • Child Clone
  • Vector Type
    Plasmid
  • Insert Site
    EcoRI
  • Insert Size
    1.124kb
  • Synonyms
    BMP-2a probe
Source
  • Species
    mouse, laboratory
Genes
Bmp2 bone morphogenetic protein 2
Expression
  • Assay Results
    206
Polymorphisms
J:1371 Hess EJ, et al., J Neurosci. 1992 Jul;12(7):2865-74
Endonuclease Gene Allele Fragments Strains
XbaI Bmp2 m 4.6,~8kb M. m. musculus
s ~7.5,~15kb M. spretus
References
J:15320 Lyons KM, et al., Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development. Genes Dev. 1989 Nov;3(11):1657-68
J:32952 Lyons KM, et al., Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development. 1990 Aug;109(4):833-44
J:1371 Hess EJ, et al., Spontaneous locomotor hyperactivity in a mouse mutant with a deletion including the Snap gene on chromosome 2. J Neurosci. 1992 Jul;12(7):2865-74
J:22224 Yamaji N, et al., A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4. Biochem Biophys Res Commun. 1994 Dec 30;205(3):1944-51
J:25144 Lyons KM, et al., Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech Dev. 1995 Mar;50(1):71-83
J:29484 Bennett JH, et al., Bone morphogenetic protein-2 and -4 expression during murine orofacial development. Arch Oral Biol. 1995 Sep;40(9):847-54
J:29671 Bitgood MJ, et al., Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol. 1995 Nov;172(1):126-38
J:34068 Constam DB, et al., SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. J Cell Biol. 1996 Jul;134(1):181-91
J:34307 Loomis CA, et al., The mouse Engrailed-1 gene and ventral limb patterning. Nature. 1996 Jul 25;382(6589):360-3
J:39018 Dudley AT, et al., Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos. Dev Dyn. 1997 Mar;208(3):349-62
J:39658 Buscher D, et al., Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development. Mech Dev. 1997 Mar;62(2):175-82
J:41080 Furuta Y, et al., Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development. 1997 Jun;124(11):2203-12
J:49653 Yang Y, et al., Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling. Development. 1998 Aug;125(16):3123-32
J:49808 Crackower MA, et al., Defect in the maintenance of the apical ectodermal ridge in the Dactylaplasia mouse. Dev Biol. 1998 Sep 1;201(1):78-89
J:50462 Dassule HR, et al., Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol. 1998 Oct 15;202(2):215-27
J:54066 Dupe V, et al., Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev Biol. 1999 Apr 1;208(1):30-43
J:59923 Tole S, et al., Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J). Dev Biol. 2000 Jan 15;217(2):254-65
J:60094 Kanzler B, et al., BMP signaling is essential for development of skeletogenic and neurogenic cranial neural crest. Development. 2000 Mar;127(5):1095-104
J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
J:79931 Ohkubo Y, et al., Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles. Neuroscience. 2002;111(1):1-17
J:103164 Minina E, et al., Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109
J:121318 Davis SW, et al., Noggin regulates Bmp4 activity during pituitary induction. Dev Biol. 2007 May 1;305(1):145-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory