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Gene Expression Data
Assay Details
Assay
Reference: J:171497 Huang HP, et al., Gene targeting and expression analysis of mouse Tem1/endosialin using a lacZ reporter. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):316-26
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5439317
Gene symbol: Cd248
Gene name: CD248 antigen, endosialin
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 8.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS13: embryo Absent 2A
Specimen 2B: embryonic day 9.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Present 2B
TS15: head mesenchyme Present 2B
TS15: outflow tract Present 2B
TS15: sinus venosus Present 2B
Specimen 2C: embryonic day 9.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Strong 2C
Specimen 2D: embryonic day 9.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS15: common atrial chamber Present 2D
TS15: outflow tract Present 2D
TS15: sinus venosus Present 2D
TS15: branchial arch artery Present 2D Authors report expression in the aortic arch.
Specimen 2E: embryonic day 9.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component mesenchyme Weak 2E
Specimen 2F: embryonic day 9.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 2F Authors report expression in cephalic mesenchyme and its blood vessels.
Specimen 3A: embryonic day 10.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS17: dorsal aorta Strong 3A
TS17: 1st branchial arch mandibular component mesenchyme Weak 3A
TS17: heart Weak 3A
Specimen 3B: embryonic day 10.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS17: head mesenchyme Present Regionally restricted 3B Authors report expression in some vascular walls in the cephalic mesenchyme. Weaker expression in cephalic mesenchyme.
Specimen 3C: embryonic day 11.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS19: 2nd branchial arch Strong 3C
TS19: dorsal aorta Strong 3C
TS19: head mesenchyme Strong 3C
TS19: midgut mesenchyme Strong 3C
TS19: 1st branchial arch Strong Regionally restricted 3C Expression in mandibular component of first branchial arch.
TS19: blood vessel Strong Regionally restricted 3C Expression in the oropharynx, abdominal wall and umbilical blood vessels.
TS19: body wall Strong Regionally restricted 3C Expression in the oropharynx, abdominal wall and umbilical blood vessels.
TS19: pharynx Strong Regionally restricted 3C Expression in the oropharynx, abdominal wall and umbilical blood vessels.
Specimen 3D: embryonic day 11.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS19: common cardinal vein Present 3D
TS19: lung mesenchyme Present 3D
TS19: midgut mesenchyme Present 3D
TS19: septum transversum Present 3D
TS19: liver Present Regionally restricted 3D Expression in surface of liver primordium
TS19: urogenital sinus Present Regionally restricted 3D Expression in mesenchyme around the cystic primordium.
TS19: body wall Present Regionally restricted 3D Expression in thoracic and abdominal body walls.
Specimen 3E: embryonic day 12.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS20: dorsal aorta Present 3E
TS20: genital tubercle Present 3E
TS20: head mesenchyme Present 3E
TS20: body wall Present Regionally restricted 3E Expression in the thoracic body wall
TS20: heart Weak 3E
TS20: liver Weak Regionally restricted 3E Decreased expression in the peripheral liver, and mesenchyme surrounding lung and midgut.
TS20: lung mesenchyme Weak Regionally restricted 3E Decreased expression in the peripheral liver, and mesenchyme surrounding lung and midgut.
TS20: midgut mesenchyme Weak Regionally restricted 3E Decreased expression in the peripheral liver, and mesenchyme surrounding lung and midgut.
Specimen 3F: embryonic day 12.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS20: mesonephros Weak Diffuse 3F
Specimen 4A: embryonic day 13.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS21: vibrissa follicle Strong 4A
Specimen 4B: embryonic day 13.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS21: nose Strong Regionally restricted 4B High expression in mesenchymal tissues of nose
TS21: genital tubercle Strong 4B
TS21: blood vessel Strong Regionally restricted 4B High expression in the vascular walls of umbilical vessels.
Specimen 4C: embryonic day 14.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS22: genital tubercle Strong 4C
TS22: lower lip Strong 4C
TS22: tongue Strong 4C
TS22: tooth Strong 4C
TS22: body wall Strong Regionally restricted 4C Strong expression the thoracic and abdominal body wall.
TS22: blood vessel Strong Regionally restricted 4C Strong expression in umbilical blood vessels.
TS22: dermis Strong Regionally restricted 4C Strong expression in the dermis of the back.
Specimen 4D: embryonic day 14.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS22: cornea Strong 4D
TS22: extrinsic ocular muscle Strong 4D Authors report strong expression in mesodermal condensation of the eye (future extrinsic ocular muscle).
Specimen 4E: embryonic day 14.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS22: lung mesenchyme Present Regionally restricted 4E Expression in 1-2 layers of mesenchymal cells surrounding the bronchi.
Specimen 4F: embryonic day 14.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS22: mesonephros Weak 4F
Specimen 4G: embryonic day 16.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS24: maturing glomerular tuft Strong 4G
TS24: renal small blood vessel Strong Regionally restricted 4G Strong expression in small arteries of the kidney.
Specimen 4H: embryonic day 16.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS24: lobar bronchus Strong 4H Strong expression in small arteries of the kidney.
Specimen 5A: embryonic day 17.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS25: glomerular tuft Strong 5A
TS25: renal small blood vessel Strong Regionally restricted 5A Strong expression in some vascular walls in the kidney.
Specimen not shown: embryonic day 17.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS25: liver Trace Barely detectable expression in the liver.
Specimen 5B lacZ/lacZ: embryonic day 17.5; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS25: liver vascular element Weak Regionally restricted 5B Weak expression in intrahepatic venular wall.
Specimen not shown: postnatal day 1; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS27: glomerular tuft Strong
Specimen 5C: postnatal day 1; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS27: spleen Present Regionally restricted 5C Expression in wall of large vessels in the spleen.
Specimen 5D: postnatal day 1; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS27: lung vascular element Present Regionally restricted 5D Expression in some vessels of pulmonary alveolar wall.
Specimen 5E: postnatal day 1; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS27: vibrissa Present Regionally restricted 5E Expression in dermis stroma around whisker follicles
Specimen 5F: postnatal day 80; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS28: metanephros Strong 5F
Specimen 5G: postnatal day 80; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS28: glomerular tuft Strong Regionally restricted 5G Stronger expression in glomeruli in the cortex than in the medulla.
Specimen 5H: postnatal day 80; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS28: vasculature of oviduct Moderate 5H
Specimen 6A: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: estrus stage
Structure Level Pattern Image Note
TS28: endometrium stroma Present Scattered 6A
Specimen 6B: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: estrus stage
Structure Level Pattern Image Note
TS28: endometrium stroma Present Scattered 6B
Specimen 6C: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: metestrus stage
Structure Level Pattern Image Note
TS28: endometrium stroma Strong 6C
TS28: endometrium Strong Regionally restricted 6C Expression in vessels of surface endometrium.
Specimen 6D: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: metestrus stage
Structure Level Pattern Image Note
TS28: endometrium stroma Strong 6D
TS28: endometrium Strong Regionally restricted 6D Expression in vessels of surface endometrium.
Specimen 6E: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: diestrus stage
Structure Level Pattern Image Note
TS28: endometrium stroma Present Scattered 6E
Specimen 6F: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: diestrus stage
Structure Level Pattern Image Note
TS28: endometrium stroma Present Scattered 6F
Specimen 6G: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: proestrus stage
Structure Level Pattern Image Note
TS28: uterus Strong Regionally restricted 6G Expression in endometrial-myometrial junction and middle muscular layer.
Specimen 6H: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: proeestrus stage
Structure Level Pattern Image Note
TS28: uterus Strong Regionally restricted 6H Expression in endometrial-myometrial junction and middle muscular layer.
TS28: endometrium glandular epithelium Weak Regionally restricted 6H Rare expression in a few glandular cells.
Specimen 7C beta-gal: postnatal adult; Cd248tm1.1Isyu/Cd248+ (more )
Note: Double labeled: blue - Cd248 reporter; green - Vim (assay MGI:5439323).
Structure Level Pattern Image Note
TS28: glomerular tuft Present Regionally restricted 7C merged , 7C beta-gal Authors report expression in almost all vimentin-positive podocytes.
Specimen S1A lacZ/lacZ: embryonic day 8.5; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS13: embryo Absent S1A lacZ/lacZ
Specimen S1B lacZ/lacZ: embryonic day 10.5; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS17: dorsal aorta Moderate S1B lacZ/lacZ
TS17: 1st branchial arch mandibular component mesenchyme Weak S1B lacZ/lacZ
TS17: blood vessel Weak Regionally restricted S1B lacZ/lacZ Expression in umbilical vessels.
Specimen S1C lacZ/lacZ: embryonic day 11.5; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS19: dorsal aorta Strong S1C lacZ/lacZ
TS19: head mesenchyme Strong S1C lacZ/lacZ
TS19: body wall Strong Regionally restricted S1C lacZ/lacZ Expression in the thoracic body wall
TS19: urinary system Strong Regionally restricted S1C lacZ/lacZ Expression in the urogenital ridge.
TS19: blood vessel Strong Regionally restricted S1C lacZ/lacZ Expression in umbilical blood vessels.
Specimen S2A +/lacZ: embryonic day 12.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS20: dermis Present S2A +/lacZ
Specimen S2A lacZ/lacZ: embryonic day 12.5; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS20: dermis Strong S2A lacZ/lacZ Stronger staining in dermis than seen in the +/lacZ embryo.
Specimen S2B +/lacZ: embryonic day 13.5; Cd248tm1.1Isyu/Cd248+ (more )
Structure Level Pattern Image Note
TS21: dermis Present S2B +/lacZ
TS21: head mesenchyme Present S2B +/lacZ
TS21: tooth Present S2B +/lacZ
Specimen S2B lacZ/lacZ: embryonic day 13.5; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS21: genital tubercle Present S2B lacZ/lacZ
TS21: head mesenchyme Present S2B lacZ/lacZ
TS21: lip Present S2B lacZ/lacZ
TS21: tongue Present S2B lacZ/lacZ
TS21: tooth Present S2B lacZ/lacZ
TS21: body wall Present Regionally restricted S2B lacZ/lacZ Expression in 1-2 layers of mesenchymal cells surrounding the bronchi.
TS21: blood vessel Present Regionally restricted S2B lacZ/lacZ Expression in umbilical blood vessels.
Specimen S3A: postnatal; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS28: vibrissa follicle Present Regionally restricted S3A Expression in dermis stroma and dermal papillae of whisker follicles.
Specimen S3B: postnatal; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS28: glomerular tuft Strong S3B
Specimen S3C: postnatal; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS28: epididymis Weak Regionally restricted S3C Weak expression in stroma of epididymis.
Specimen S3D: postnatal; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS28: heart Weak Regionally restricted S3D Weak expression in some small heart vessels.
Specimen S3E: postnatal day 80; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS28: lung Trace Regionally restricted S3E Occasional trace expression in small blood vessels of the lung.
Specimen S3F: postnatal day 80; Cd248tm1.1Isyu/Cd248tm1.1Isyu (more )
Structure Level Pattern Image Note
TS28: heart Trace Regionally restricted S3F Occasional trace expression in small blood vessels of the heart.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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