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Cd248tm1.1Isyu
Targeted Allele Detail
Summary
Symbol: Cd248tm1.1Isyu
Name: CD248 antigen, endosialin; targeted mutation 1.1, I-Shing Yu
MGI ID: MGI:4950376
Synonyms: Tem1-lacZ
Gene: Cd248  Location: Chr19:5118106-5120668 bp, + strand  Genetic Position: Chr19, 4.24 cM
Alliance: Cd248tm1.1Isyu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171497
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region was replaced with lacZ and a floxed neo cassette. Cre-mediated recombination removed the neo cassette. (J:171497)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 113 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd248 Mutation:  24 strains or lines available
References
Original:  J:171497 Huang HP, et al., Gene targeting and expression analysis of mouse Tem1/endosialin using a lacZ reporter. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):316-26
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory