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Gene Expression Data
Assay Details
Assay
Reference: J:29935 Dehni G, et al., TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination. Mech Dev. 1995 Nov;53(3):369-81
Assay type: RNA in situ
MGI Accession ID: MGI:5438637
Gene symbol: Tle3
Gene name: transducin-like enhancer of split 3
Probe: TLE3 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen Not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trunk unsegmented mesenchyme Present Regionally restricted Expression is present in the posterior presomitic mesoderm subjacent to neural plate tissue at the caudal extremity of the primitive streak region.

Specimen 2A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Present 2A
TS15: head mesenchyme Present 2A
TS15: 1st branchial arch Present 2A
TS15: 2nd branchial arch Present 2A
TS15: central nervous system Weak 2A There is low expression in the neuroepithelium.

Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: somite Present Non-Uniform 2B Expression is very low in recently condensed epithelial somites. It is more readily detectable in more mature somites.

Specimen 2C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk sclerotome Present 2C Expression is present in the ventral mesenchyme, in cells lateral to the notochord. This pattern extends along the anteroposterior axis to the level of the most occipital somites.
TS17: embryo Present Regionally restricted 2C Expression is present in cell dorsolateral to the spinal cord; these are believed to be neural crest cells.
TS17: trunk dermomyotome Present Regionally restricted 2C Expression is present in the dorsal epithelial cells. This pattern extends along the anteroposterior axis to the level of the most occipital somites.
TS17: notochord Absent 2C

Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: C1 vertebra Present 3B
TS22: C2 vertebra Present 3B
TS22: intervertebral disc Present 3B
TS22: vertebral cartilage condensation Present 3B
TS22: central nervous system Strong 3B

Specimen 3D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intervertebral disc Present 3D
TS24: vertebra Present 3D
TS24: dorsal root ganglion Present Non-Uniform 3D Expression is found predominantly in cells located around the periphery.
TS24: skin Present 3D

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present 5B Expression is present in the neuroepithelium.
TS20: diencephalon Present 5B
TS20: head mesenchyme Present 5B
TS20: medulla oblongata alar plate Present 5B
TS20: skin Present 5B Expression is present in the surface ectoderm.

Specimen 5D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon Present 5D Expression is present in the neuroepithelium.
TS22: corpus striatum Present 5D
TS22: cerebellum Present 5D
TS22: diencephalon Present 5D
TS22: metencephalon Present 5D
TS22: medulla oblongata alar plate Present 5D

Specimen 5F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Present 5F
TS24: cerebral cortex subventricular zone Present 5F
TS24: cerebral cortex ventricular layer Present 5F
TS24: cortical plate Present Non-Uniform 5F Expression is present in more external layers of cells in the cortical plate.
TS24: skin Present 5F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory