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Gene Expression Data
Assay Details
Assay
Reference: J:63194 Tsang TE, et al., Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo. Dev Biol. 2000 Jul 1;223(1):77-90
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5435303
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Reporter: lacZ
Direct Detection
Results
Specimen 2A +/-: embryonic day 8.5; Lhx1tm1Tmj/Lhx1+ (more )
Note: Early somite stage.
Structure Level Pattern Image Note
TS13: somatopleure Present 2A left
TS13: splanchnopleure Present 2A left
TS13: node Present 2A left Expression is present in posterior midline tissues.
TS13: notochord Present 2A left Expression is present in posterior midline tissues.

Specimen 2A -/-: embryonic day 8.5; Lhx1tm1Tmj/Lhx1tm1Tmj (more )
Note: Early somite stage.
Structure Level Pattern Image Note
TS13: somatopleure Present 2A right Expression is stronger in the somatopleure than in the splanchnopleure.
TS13: splanchnopleure Present 2A right Expression is stronger in the somatopleure than in the splanchnopleure.

Specimen 2B +/-: embryonic day 8.5; Lhx1tm1Tmj/Lhx1+ (more )
Note: Early somite stage.
Structure Level Pattern Image Note
TS13: somatopleure Present 2B left
TS13: splanchnopleure Present 2B left

Specimen 2B -/-: embryonic day 8.5; Lhx1tm1Tmj/Lhx1tm1Tmj (more )
Note: Early somite stage.
Structure Level Pattern Image Note
TS13: somatopleure Present 2B right Expression is stronger in the somatopleure than in the splanchnopleure.
TS13: splanchnopleure Present 2B right Expression is stronger in the somatopleure than in the splanchnopleure.

Specimen 2C +/-: embryonic day 9.5; Lhx1tm1Tmj/Lhx1+ (more )
Note: Forelimb bud stage.
Structure Level Pattern Image Note
TS15: nephrogenic cord Present 2C left Expression is present in the nephrogenic cord (nephric duct and blastema).

Specimen 2C -/-: embryonic day 9.5; Lhx1tm1Tmj/Lhx1tm1Tmj (more )
Note: Forelimb bud stage.
Structure Level Pattern Image Note
TS15: trunk mesenchyme Present Regionally restricted 2C right Expression is present in the body wall. Midtrunk, expression is present in clusters of necrotic cells in the intermediate mesoderm (presumaby disorganized and degenerate nephrogenic tissues); it is absent in more caudal regions.
TS15: notochord Present Regionally restricted 2C right Expression is present in the posterior notochord.

Specimen 2D +/-: embryonic day 9.5; Lhx1tm1Tmj/Lhx1+ (more )
Note: Forelimb bud stage.
Structure Level Pattern Image Note
TS15: nephrogenic cord Present 2D left Expression is present in the nephrogenic cord (nephric duct and blastema).

Specimen 2D -/-: embryonic day 9.5; Lhx1tm1Tmj/Lhx1tm1Tmj (more )
Note: Forelimb bud stage.
Structure Level Pattern Image Note
TS15: trunk mesenchyme Present Regionally restricted 2D right Midtrunk, expression is present in clusters of necrotic cells in the intermediate mesoderm (presumaby disorganized and degenerate nephrogenic tissues); it is absent in more caudal regions.

Specimen Not shown: embryonic day 9.5; Lhx1tm1Tmj/Lhx1tm1Tmj (more )
Note: Forelimb bud stage.
Structure Level Pattern Image Note
TS15: nephric duct Present The duct is rudimentary in appearance.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory