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Gene Expression Data
Assay Details
Assay
Reference: J:86943 Lauren J, et al., Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems. Mol Cell Neurosci. 2003 Nov;24(3):581-94
Assay type: RNA in situ
MGI Accession ID: MGI:5316511
Gene symbol: Rtn4r
Gene name: reticulon 4 receptor
Probe: NGR cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Strong 4A
TS21: inferior glossopharyngeal ganglion Strong 4A
TS21: inferior vagus ganglion Strong 4A
TS21: peripheral nervous system Strong 4A
TS21: trigeminal ganglion Strong 4A
TS21: vestibulo-cochlear ganglion Strong 4A
TS21: cortical plate Present 4A
TS21: brainstem Present Regionally restricted 4A
TS21: spinal cord Present Regionally restricted 4A
Specimen 4D,E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: spinal cord gray matter Present 4E , 4D
TS27: dorsal root ganglion Strong 4D , 4E
TS27: sympathetic ganglion Weak 4D , 4E
Specimen 5A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Strong 5A
TS28: anterior olfactory nucleus Strong 5A
TS28: cortical layer II Strong 5A
TS28: cortical layer III Strong 5A
TS28: cortical layer IV Strong 5A
TS28: cortical layer V Strong 5A
TS28: cortical layer VI Strong 5A
TS28: habenula Strong 5A
TS28: hippocampal formation Strong 5A
TS28: main olfactory bulb mitral cell layer Strong 5A
TS28: midbrain Present 5A
TS28: brainstem Present Widespread 5A
TS28: hypothalamus Trace Regionally restricted 5A There is no or very low levels of expression.
Specimen 5B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong Regionally restricted 5B
TS28: cortical layer III Strong Regionally restricted 5B
TS28: cortical layer IV Strong Regionally restricted 5B
TS28: cortical layer V Strong Regionally restricted 5B
TS28: cortical layer VI Strong Regionally restricted 5B
TS28: caudate-putamen Absent 5B
TS28: lateral septal nucleus Absent 5B
Specimen 5C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 5C
TS28: cortical layer III Strong 5C
TS28: cortical layer IV Strong 5C
TS28: cortical layer V Strong 5C
TS28: cortical layer VI Strong 5C
TS28: hippocampal formation Strong 5C
TS28: amygdala Present 5C
TS28: medial habenular nucleus Present 5C
TS28: thalamus Present 5C
Specimen 6A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 6A
Specimen 6B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: anterior olfactory nucleus Present 6B
TS28: cerebral cortex Present 6B
TS28: main olfactory bulb mitral cell layer Present 6B
Specimen 6C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: spinal cord dorsal horn Present 6C
Specimen 6D,E,F: postnatal adult (more )
Note: (D,E) Brightfield/dark field pair. (F) is a higher magnification of (E).
Structure Level Pattern Image Note
TS28: corpus callosum Present 6E , 6D , 6F Expression is in neurons, absent in oligodendrocytes.
TS28: cortical layer III Present 6E , 6D , 6F Expression is in neurons, absent in oligodendrocytes.
TS28: cortical layer IV Present 6E , 6D , 6F Expression is in neurons, absent in oligodendrocytes.
TS28: cortical layer V Present 6E , 6D , 6F Expression is in neurons, absent in oligodendrocytes.
TS28: cortical layer VI Present 6E , 6D , 6F Expression is in neurons, absent in oligodendrocytes.
Specimen 6G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Strong 6G
Specimen Table 1: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Strong
TS28: amygdala Strong
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cortical layer IV Strong
TS28: cortical layer V Strong
TS28: cortical layer VI Strong
TS28: dentate gyrus granule cell layer Strong
TS28: gigantocellular reticular nucleus Strong
TS28: medial habenular nucleus Strong
TS28: piriform cortex Strong
TS28: pontine nucleus Strong
TS28: reticular tegmental nucleus Strong
TS28: hippocampus CA2 Strong Regionally restricted Expression is in pyramidal cell layers.
TS28: hippocampus CA3 Strong Regionally restricted Expression is in pyramidal cell layers.
TS28: thalamus Strong Regionally restricted Expression is in the medial habenula and most other nuclei.
TS28: telencephalon Moderate Regionally restricted Expression is in periglomerular cells and the mitral cell layer and is absent in the internal granular layer.
TS28: brainstem Moderate Regionally restricted Expression is in the lateral lemniscus.
TS28: anterior olfactory nucleus Moderate
TS28: cerebellum granule cell layer Moderate
TS28: cochlear nucleus Moderate
TS28: cuneate nucleus Moderate
TS28: dorsal root ganglion Moderate
TS28: inferior olivary nucleus Moderate
TS28: locus coeruleus Moderate
TS28: nucleus of trapezoid body Moderate
TS28: red nucleus Moderate
TS28: spinal cord dorsal horn Moderate
TS28: spinal vestibular nucleus Moderate
TS28: trigeminal V mesencephalic nucleus Moderate
TS28: trigeminal ganglion Moderate
TS28: telencephalon septum Moderate Regionally restricted Expression is in the triangular septal nucleus.
TS28: cerebellum Moderate Regionally restricted Expression is in lateral and medial cerebellar nuclei.
TS28: hypothalamus Weak Regionally restricted Expression is in mamillary and premammillary nuclei.
TS28: inferior colliculus Weak
TS28: spinal cord ventral horn Weak
TS28: substantia nigra Weak
TS28: superior colliculus Weak
TS28: trigeminal V sensory nucleus Weak
TS28: arcuate nucleus Absent
TS28: caudate-putamen Absent
TS28: cerebellum Purkinje cell layer Absent
TS28: choroid plexus Absent
TS28: globus pallidus Absent
TS28: interpeduncular nucleus Absent
TS28: lateral septal complex Absent
TS28: pallidum Absent
TS28: septofimbrial nucleus Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/09/2025
MGI 6.24 		The Jackson Laboratory