About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:80020 Marcil A, et al., Pitx1 and Pitx2 are required for development of hindlimb buds. Development. 2003 Jan;130(1):45-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5298114
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Antibody: P2R10
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 7A: embryonic day 8.0 (more )
Note: This specimen is at the 7 somite stage.
Structure Level Pattern Image Note
TS12: head Present 7A bottom There is bilateral expression in the head.
TS12: lateral plate mesoderm Present Regionally restricted 7A bottom Expression is present in the left lateral plate mesoderm. In the tail, stronger expression is found on the left side but expression on the right side is still significant.
Specimen 7B: embryonic day 8.5 (more )
Note: This specimen is at the 11 somite stage.
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 7B bottom Expression is present in the left lateral plate mesoderm. In the tail, stronger expression is found on the left side but expression on the right side is still significant.
Specimen 7C: embryonic day 9.0 (more )
Note: This specimen is at the 15 somite stage.
Structure Level Pattern Image Note
TS14: head Present 7C bottom There is bilateral expression in the head.
TS14: mesenchyme derived from lateral plate Present Regionally restricted 7C bottom Expression is present in the left lateral plate mesoderm.
Specimen 7D: embryonic day 9.0 (more )
Note: This specimen is at the 15 somite stage.
Structure Level Pattern Image Note
TS14: tail bud Present Non-Uniform 7D bottom Stronger expression is found on the left side but expression on the right side is still significant.
Specimen 7E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Absent 7E middle
Specimen 7F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 7F middle Expression is present in muscle cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory