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Gene Expression Data
Assay Details
Assay
Reference: J:80020 Marcil A, et al., Pitx1 and Pitx2 are required for development of hindlimb buds. Development. 2003 Jan;130(1):45-55
Assay type: RNA in situ
MGI Accession ID: MGI:5298010
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe33
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5B left: embryonic day 10.5 (more )
Note: This specimen is at the 37-somite stage.
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present Regionally restricted 5B left Expression is present in the zone of polarizing activity, which occupies the posterior quadrant of the hindlimb.
Specimen 5B middle: embryonic day 10.5; Pitx1tm1Jdr/Pitx1tm1Jdr (more )
Note: This specimen is at the 37-somite stage.
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present Regionally restricted 5B middle Expression is present in the zone of polarizing activity, which occupies the posterior quadrant of the hindlimb.
Specimen 5B right: embryonic day 10.5; Pitx1tm1Jdr/Pitx1tm1Jdr, Pitx2tm2Sac/Pitx2+ (more )
Note: This specimen is at the 38-somite stage.
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present Regionally restricted 5B right Expression is present in the zone of polarizing activity, which extends all the way up to half the hindlimb in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory