Gene Expression Data
Assay Details
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Assay
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Reference:
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J:4501
Mansour SL, et al., Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development. 1993 Jan;117(1):13-28
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5050137
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Gene symbol:
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Fgf3
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Gene name:
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fibroblast growth factor 3
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Reporter:
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lacZ
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Direct Detection
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Assay notes:
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Embryos (21-25 somites) were fixed in 2% formaldehyde for 6 minutes.
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Results
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Specimen
6C:
embryonic day 9.5; Fgf3tm2Mrc/Fgf3 +
(more  )
Specimen
6C:
(close  )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Fgf3tm2Mrc/Fgf3+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: central nervous system |
Present |
Regionally restricted |
6C
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A short segment of the neural tube, immediately adjacent to the otocyst, was the only expression region in the embryo.
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Specimen
6D:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Fgf3tm2Mrc/Fgf3tm1Mrc
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: central nervous system |
Present |
Regionally restricted |
6D
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A short segment of the neural tube, immediately adjacent to the otocyst, was the only expression region in the embryo.
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Specimen
6E:
embryonic day 9.5; Fgf3tm2Mrc/Fgf3 +
(more )
Note: Double labeled: blue - Fgf3 reporter; brown - Nefm (assay MGI:5050134).
Specimen
6E:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Fgf3tm2Mrc/Fgf3+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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Note:
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Double labeled: blue - Fgf3 reporter; brown - Nefm (assay MGI:5050134).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: central nervous system |
Present |
Regionally restricted |
6E
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A short segment of the neural tube, immediately adjacent to the otocyst, was the only expression region in the embryo.
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Specimen
6F:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Fgf3tm2Mrc/Fgf3tm1Mrc
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Formaldehyde
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Note:
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Double labeled: blue - Fgf3 reporter; brown - Nefm (assay MGI:5050134).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: central nervous system |
Present |
Regionally restricted |
6F
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A short segment of the neural tube, immediately adjacent to the otocyst, was the only expression region in the embryo.
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Specimen
6G:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Fgf3tm2Mrc/Fgf3tm1Mrc
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Note:
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Double labeled: blue - Fgf3 reporter; brown - Nefm (assay MGI:5050134).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: rhombomere 5 |
Present |
Regionally restricted |
6G
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Expression was along the luminal and pial surfaces as shown in this coronal section taken through the ventral region of the otocyst.
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| TS15: rhombomere 6 |
Present |
Regionally restricted |
6G
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Expression was along the luminal and pial surfaces as shown in this coronal section taken through the ventral region of the otocyst.
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