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Gene Expression Data
Assay Details
Assay
Reference: J:147759 Tan M, et al., RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6203-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4948710
Gene symbol: Cdkn1b
Gene name: cyclin dependent kinase inhibitor 1B
Antibody: anti-p27
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3G +/+: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo Absent 3G +/+
Specimen 3G gt/gt: embryonic day 6.5; Rbx1Gt(XB674)Byg/Rbx1Gt(XB674)Byg (more )
Structure Level Pattern Image Note
TS9: embryo Present 3G gt/gt There is a dramatic accumulation of the protein in mutants compared to wild type.
Specimen 5D left: embryonic day 6.5; Cdkn1btm1Mlf/Cdkn1b+ (more )
Structure Level Pattern Image Note
TS9: embryo Absent 5D left panel
Specimen 5D right: embryonic day 6.5; Cdkn1btm1Mlf/Cdkn1btm1Mlf, Rbx1Gt(XB674)Byg/Rbx1Gt(XB674)Byg (more )
Structure Level Pattern Image Note
TS9: embryo Absent 5D right panel
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory