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Gene Expression Data
Assay Details
Assay
Reference: J:138858 Georgas K, et al., Use of dual section mRNA in situ hybridisation/immunohistochemistry to clarify gene expression patterns during the early stages of nephron development in the embryo and in the mature nephron of the adult mouse kidney. Histochem Cell Biol. 2008 Nov;130(5):927-42
Assay type: RNA in situ
MGI Accession ID: MGI:4849242
Gene symbol: Umod
Gene name: uromodulin
Probe: RIKEN clone D630003D16 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7Aa: postnatal adult (more )
Structure Level Pattern Image Note
TS28: outer renal medulla Present 7Ab , 7Aa
Specimen 7Ac: postnatal adult (more )
Note: Double labeled: blue - Umod; orange - Aqp1 (assay MGI:4849228).
Structure Level Pattern Image Note
TS28: outer renal medulla Present 7Ac
Specimen 7Ad: postnatal adult (more )
Note: Double labeled: blue - Umod; orange - Aqp1 (assay MGI:4849228).
Structure Level Pattern Image Note
TS28: distal convoluted tubule Present 7Ad
Specimen 7Ae: postnatal adult (more )
Note: Double labeled: blue - Umod; orange - Aqp1 (assay MGI:4849228).
Structure Level Pattern Image Note
TS28: distal straight tubule of outer stripe of outer medulla Present 7Ae
Specimen 7Af: postnatal adult (more )
Note: Double labeled: blue - Umod; orange - Aqp1 (assay MGI:4849228).
Structure Level Pattern Image Note
TS28: premacula segment of distal straight tubule of outer medulla Present 7Af
Specimen 7Ag: postnatal adult (more )
Note: Double labeled: blue - Umod; orange - Aqp1 (assay MGI:4849228).
Structure Level Pattern Image Note
TS28: premacula segment of distal straight tubule of inner stripe of inner medulla Present 7Ag
Specimen 7Ba: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: medullary renal tubule Present 7Bb , 7Ba Expression is present in tubules of Stage IV nephrons of medulla.
Specimen 7Bc: embryonic day 15.5 (more )
Note: Double labeled: blue - Umod; orange - Aqp1 (assay MGI:4849228).
Structure Level Pattern Image Note
TS23: immature loop of Henle Strong 7Bc
Specimen 7Bd: embryonic day 15.5 (more )
Note: Double labeled: blue - Umod; orange - Aqp1 (assay MGI:4849228).
Structure Level Pattern Image Note
TS23: immature loop of Henle ascending limb Strong 7Bd
Specimen 7C: embryonic day 15.5 (more )
Note: This schematic summarizes the gene expression data in stage IV nephrons.
Structure Level Pattern Image Note
TS23: immature loop of Henle ascending limb Strong 7C Umod
Specimen 7C: postnatal adult (more )
Note: This schematic summarizes the gene expression data in stage IV nephrons.
Structure Level Pattern Image Note
TS28: thin ascending limb of medulla Strong 7C Umod
TS28: premacula segment of distal straight tubule of outer medulla Strong 7C Umod Expression is present in the distal straight tubule.
TS28: distal convoluted tubule Strong 7C Umod
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory