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Gene Expression Data
Assay Details
Assay
Reference: J:92504 Harfe BD, et al., Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell. 2004 Aug 20;118(4):517-28
Assay type: RNA in situ
MGI Accession ID: MGI:4838797
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe66
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Strong Regionally restricted 1A Expression is observed in the posterior border of the distal limb bud.
Specimen 2A: embryonic day 11.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS18: forelimb bud Present Regionally restricted 2A Expression is observed in a small region of the posterior portion of the limb bud.
Specimen 6C: embryonic day 10.5; Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present 6C Expression is observed in the posterior region of the hindlimb bud.
Specimen 6D: embryonic day 10.5; Disp1icb/Disp1tm1Amc, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: hindlimb bud Present 6D There is no change in expression in the mutant embryo.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory