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Gene Expression Data
Assay Details
Assay
Reference: J:164031 Pleiser S, et al., Expression patterns of the mouse Spir-2 actin nucleator. Gene Expr Patterns. 2010 October - December;10(7-8):345-350
Assay type: RNA in situ
MGI Accession ID: MGI:4837339
Gene symbol: Spire2
Gene name: spire type actin nucleation factor 2
Probe: pcDNA3-m-Spir-2-NT
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3a E11.5 left: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Strong 3a E11.5 left
TS19: future spinal cord Strong 3a E11.5 left
TS19: hindbrain Strong 3a E11.5 left
TS19: midbrain Strong 3a E11.5 left
TS19: 3rd ventricle Present 3a E11.5 left
TS19: dorsal root ganglion Present 3a E11.5 left
TS19: mesencephalic vesicle Present 3a E11.5 left
Specimen 3a E11.5 right: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Strong 3a E11.5 right
TS19: future spinal cord Strong 3a E11.5 right
TS19: hindbrain Strong 3a E11.5 right
TS19: midbrain Strong 3a E11.5 right
TS19: dorsal root ganglion Present 3a E11.5 right
Specimen 3a E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forebrain Strong 3a E13.5
TS21: hindbrain Strong 3a E13.5
TS21: midbrain Strong 3a E13.5
TS21: spinal cord Strong 3a E13.5
TS21: dorsal root ganglion Present 3a E13.5
Specimen 3a E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Strong 3a E15.5
TS23: hindbrain Strong 3a E15.5
TS23: midbrain Strong 3a E15.5
TS23: spinal cord Strong 3a E15.5
TS23: retina Strong Regionally restricted 3a E15.5 Expression is in the postmitotic retina in retinal ganglion cells.
TS23: dorsal root ganglion Present 3a E15.5
TS23: intestine Absent 3a E15.5
Specimen 3a E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forebrain Strong 3a E17.5
Specimen 3b E11.5 top: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon ventricular layer Present 3b E11.5 top lateral ventricle
Specimen 3b E11.5 middle: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon ventricular layer Present 3b E11.5 middle 3rd ventricle
Specimen 3b E11.5 bottom: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present 3b E11.5 bottom mesencephalic vesicle
TS19: hindbrain Present 3b E11.5 bottom 4th ventricle
Specimen 3b E14.5 top: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain Present 3b E14.5 top Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: forebrain ventricular layer Present 3b E14.5 top Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: lateral ganglionic eminence Present 3b E14.5 top Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: cerebral cortex Strong 3b E14.5 top
TS22: thalamus Strong 3b E14.5 top
TS22: midbrain Present 3b E14.5 top
Specimen 3b E14.5 middle: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain Present 3b E14.5 middle Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: forebrain ventricular layer Present 3b E14.5 middle Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: lateral ganglionic eminence Present 3b E14.5 middle Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: cerebral cortex Strong 3b E14.5 middle
TS22: thalamus Strong 3b E14.5 middle
TS22: midbrain Present 3b E14.5 middle
Specimen 3b E14.5 bottom: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain Present 3b E14.5 bottom Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: forebrain ventricular layer Present 3b E14.5 bottom Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: lateral ganglionic eminence Present 3b E14.5 bottom Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS22: cerebral cortex Strong 3b E14.5 bottom
TS22: thalamus Strong 3b E14.5 bottom
TS22: midbrain Present 3b E14.5 bottom
Specimen 3b E17.5 top: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forebrain Present 3b E17.5 top Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: forebrain ventricular layer Present 3b E17.5 top Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: lateral ganglionic eminence Present 3b E17.5 top Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: cerebral cortex Strong 3b E17.5 top
TS25: thalamus Strong 3b E17.5 top
TS25: midbrain Present 3b E17.5 top
Specimen 3b E17.5 middle: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forebrain Present 3b E17.5 middle Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: forebrain ventricular layer Present 3b E17.5 middle Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: lateral ganglionic eminence Present 3b E17.5 middle Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: cerebral cortex Strong 3b E17.5 middle
TS25: thalamus Strong 3b E17.5 middle
TS25: midbrain Present 3b E17.5 middle
Specimen 3b E17.5 bottom: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forebrain Present 3b E17.5 bottom Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: forebrain ventricular layer Present 3b E17.5 bottom Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: lateral ganglionic eminence Present 3b E17.5 bottom Strongest expression is in the ventricular zone and lateral ganglionic eminence.
TS25: cerebral cortex Strong 3b E17.5 bottom
TS25: thalamus Strong 3b E17.5 bottom
TS25: midbrain Present 3b E17.5 bottom
TS25: hippocampus Absent 3b E17.5 bottom
Specimen 3c E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 3c E11.5 spir-2
TS19: neural tube mantle layer Present 3c E11.5 spir-2
TS19: neural tube basal columns Present Regionally restricted 3c E11.5 spir-2 Expression is in the ventral horn.
Specimen 3c E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord dorsal horn Present 3c E14.5 spir-2
TS22: spinal cord ventral horn Present 3c E14.5 spir-2
TS22: dorsal root ganglion Present 3c E14.5 spir-2
Specimen 3c E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord Present Uniform 3c E15.5 spir-2
Specimen 3d eye: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: retina Strong Regionally restricted 3d eye Expression is in the postmitotic retina in retinal ganglion cells.
Specimen 3d intestine: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: intestine Present 3d intestine
Specimen 4a: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 4a spir-2
TS28: external capsule Present 4a spir-2
TS28: inferior colliculus Present 4a spir-2
TS28: thalamus Present 4a spir-2
TS28: cerebellum Very strong 4a spir-2
Specimen 4b: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 4b
TS28: cerebellum granule cell layer Strong 4b
Specimen 4c small int. top: postnatal adult (more )
Structure Level Pattern Image Note
TS28: intestinal villus Present 4c intestine top
TS28: small intestine crypt of lieberkuhn Present 4c intestine top
Specimen 4c small int. bottom: postnatal adult (more )
Structure Level Pattern Image Note
TS28: intestinal villus Present 4c intestine bottom
TS28: small intestine crypt of lieberkuhn Present 4c intestine bottom
Specimen 4c testis top: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: spermatocyte Strong 4c testis top
TS28: spermatogonium Absent 4c testis top
TS28: Sertoli cell Sertoli cell Absent 4c testis top
TS28: Leydig cell Leydig cell Absent 4c testis top
Specimen 4c testis bottom: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: spermatocyte Strong 4c testis bottom
TS28: spermatogonium Absent 4c testis bottom
TS28: Sertoli cell Sertoli cell Absent 4c testis bottom
TS28: Leydig cell Leydig cell Absent 4c testis bottom
Specimen Not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon epithelium Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory