Bsg RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:47111 Fan QW, et al., Expression of basigin, a member of the immunoglobulin superfamily, in the mouse central nervous system. Neurosci Res. 1998 Jan;30(1):53-63
Assay type:	RNA in situ
MGI Accession ID:	MGI:4821175
Gene symbol:	Bsg
Gene name:	basigin

Probe:	Bsg cDNA8
Probe preparation:	Antisense labelled with digoxigenin RNA
Assay notes:	Probes were shortened to an average length of 150 bases.

Results

Specimen 1A: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum	Present		1A
TS28: hippocampus	Present		1A

Specimen 1C: postnatal; Bsg^tm1Tmu/Bsg^tm1Tmu (more

)

Structure	Level	Pattern	Image	Note
TS28: brain	Absent		1C

Specimen 2D: embryonic day 13.5 (more

)

Structure	Level	Image
TS21: cerebral cortex intermediate zone	Present	2D
TS21: cerebral cortex ventricular layer	Present	2D
TS21: cortical plate	Present	2D

Specimen 3A: postnatal adult (more

)

Structure	Level	Image
TS28: main olfactory bulb glomerular layer	Present	3A
TS28: main olfactory bulb mitral cell layer	Present	3A
TS28: main olfactory bulb granule cell layer	Weak	3A

Specimen 3B: postnatal adult (more

)

Structure	Level	Image
TS28: cortical layer V	Very strong	3B
TS28: piriform cortex	Very strong	3B
TS28: cerebral cortex	Present	3B
TS28: medial septal nucleus	Present	3B

Specimen 3C: postnatal adult (more

)

Structure	Level	Image
TS28: anterior dorsal thalamic nucleus	Very strong	3C
TS28: cingulate cortex	Very strong	3C
TS28: cortical layer V	Very strong	3C
TS28: paraventricular hypothalamic nucleus	Very strong	3C
TS28: piriform cortex	Very strong	3C
TS28: reticular thalamic nucleus	Very strong	3C
TS28: ventromedial hypothalamic nucleus	Very strong	3C
TS28: cerebral cortex	Present	3C
TS28: hypothalamus	Present	3C
TS28: nucleus of lateral olfactory tract	Present	3C
TS28: thalamus	Present	3C

Specimen 3D: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: amygdala	Very strong		3D
TS28: anterior dorsal thalamic nucleus	Very strong		3D
TS28: cingulate cortex	Very strong		3D
TS28: cortical layer V	Very strong		3D
TS28: paraventricular hypothalamic nucleus	Very strong		3D
TS28: piriform cortex	Very strong		3D
TS28: reticular thalamic nucleus	Very strong		3D
TS28: ventromedial hypothalamic nucleus	Very strong		3D
TS28: hippocampus CA3	Strong	Regionally restricted	3D	Strong in the pyramidal layer, weak in other regions.
TS28: hippocampus CA1	Strong	Regionally restricted	3D	Strong in the stratum oriens, weak in other regions.
TS28: cerebral cortex	Present		3D
TS28: hypothalamus	Present		3D
TS28: thalamus	Present		3D
TS28: hippocampus CA2	Weak		3D

Specimen 3E: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: anterior dorsal thalamic nucleus	Very strong		3E
TS28: cortical layer V	Very strong		3E
TS28: paraventricular hypothalamic nucleus	Very strong		3E
TS28: piriform cortex	Very strong		3E
TS28: reticular thalamic nucleus	Very strong		3E
TS28: ventromedial hypothalamic nucleus	Very strong		3E
TS28: hippocampus CA3	Strong	Regionally restricted	3E	Strong in the pyramidal layer, weak in other regions.
TS28: hippocampus CA1	Strong	Regionally restricted	3E	Strong in the stratum oriens, weak in other regions.
TS28: cerebral cortex	Present		3E
TS28: hypothalamus	Present		3E
TS28: thalamus	Present		3E
TS28: hippocampus CA2	Weak		3E

Specimen 3F: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cortical layer V	Very strong		3F
TS28: entorhinal cortex	Very strong		3F
TS28: piriform cortex	Very strong		3F
TS28: subiculum	Very strong		3F
TS28: hippocampus CA3	Strong	Regionally restricted	3F	Strong in the pyramidal layer, weak in other regions.
TS28: hippocampus CA1	Strong	Regionally restricted	3F	Strong in the stratum oriens, weak in other regions.
TS28: red nucleus	Strong		3F
TS28: substantia nigra	Strong		3F
TS28: midbrain	Strong	Regionally restricted	3F	Expression is in the interstitial nucleus mlf.
TS28: cerebral cortex	Present		3F
TS28: hippocampus CA2	Weak		3F

Specimen 3G: postnatal adult (more

)

Structure	Level	Image
TS28: dorsal raphe nucleus	Present	3G
TS28: median raphe nucleus	Present	3G
TS28: pontine nucleus	Present	3G
TS28: reticular tegmental nucleus	Present	3G
TS28: trigeminal V spinal sensory nucleus	Present	3G

Specimen 3H: postnatal adult (more

)

Structure	Level	Image
TS28: cerebellum Purkinje cell layer	Present	3H
TS28: deep cerebellar nucleus	Present	3H
TS28: dorsal raphe nucleus	Present	3H
TS28: median raphe nucleus	Present	3H
TS28: pontine nucleus	Present	3H
TS28: reticular tegmental nucleus	Present	3H
TS28: trigeminal V spinal sensory nucleus	Present	3H

Specimen 3I: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: spinal cord gray matter	Present		3I

Specimen Table 1: postnatal adult (more

)

Structure	Level	Pattern	Note
TS28: anterior dorsal thalamic nucleus	Strong
TS28: basolateral amygdaloid nucleus	Strong
TS28: cerebellum Purkinje cell layer	Strong
TS28: cortical layer V	Strong
TS28: deep cerebellar nucleus	Strong
TS28: dorsal raphe nucleus	Strong
TS28: edinger-westphal nucleus	Strong
TS28: hippocampus CA3	Strong
TS28: main olfactory bulb mitral cell layer	Strong
TS28: medial preoptic nucleus	Strong
TS28: medial septal nucleus	Strong
TS28: median raphe nucleus	Strong
TS28: nucleus of lateral olfactory tract	Strong
TS28: paraventricular hypothalamic nucleus	Strong
TS28: piriform cortex	Strong
TS28: pontine nucleus	Strong
TS28: red nucleus	Strong
TS28: reticular tegmental nucleus	Strong
TS28: reticular thalamic nucleus	Strong
TS28: retina ganglion cell layer	Strong
TS28: retina inner nuclear layer	Strong
TS28: retina outer nuclear layer	Strong
TS28: spinal cord dorsal horn	Strong
TS28: spinal cord ventral horn	Strong
TS28: supraoptic nucleus	Strong
TS28: ventromedial hypothalamic nucleus	Strong
TS28: anterior cortical amygdaloid nucleus	Moderate
TS28: cerebellum granule cell layer	Moderate
TS28: cingulate cortex	Moderate
TS28: cortical layer I	Moderate
TS28: cortical layer II	Moderate
TS28: cortical layer III	Moderate
TS28: cortical layer IV	Moderate
TS28: cortical layer VI	Moderate
TS28: entorhinal cortex	Moderate
TS28: gigantocellular reticular nucleus	Moderate
TS28: globus pallidus	Moderate
TS28: hippocampus CA1	Moderate
TS28: hippocampus CA2	Moderate
TS28: inferior colliculus	Moderate
TS28: lateral hypothalamic area	Moderate
TS28: main olfactory bulb glomerular layer	Moderate
TS28: medial amygdaloid nucleus	Moderate
TS28: medial habenular nucleus	Moderate
TS28: medial vestibular nucleus	Moderate
TS28: nucleus of diagonal band	Moderate
TS28: peduncular pontine nucleus	Moderate
TS28: subfornical organ	Moderate
TS28: superior colliculus	Moderate
TS28: trigeminal V spinal sensory nucleus	Moderate
TS28: zona incerta	Moderate
TS28: thalamus	Moderate	Regionally restricted	Expression is in mediodorsal-, ventrolateral-, ventral posterolateral-, ventral posteromedial-, and the ventrolateral and dorsomedial laterodorsal thalamic nucleus.
TS28: hypothalamus	Moderate	Regionally restricted	Expression is in anteroventral periventricular nucleus, paraventricular hypthalamic ant. parvicell., lateroanterior hyopthalamic nucelus, and anterior hypothalamic are, anterior.
TS28: basomedial amygdaloid nucleus	Weak
TS28: claustrum	Weak
TS28: dentate gyrus	Weak
TS28: dorsal cochlear nucleus	Weak
TS28: endopiriform nucleus	Weak
TS28: lateral septal nucleus	Weak
TS28: main olfactory bulb granule cell layer	Weak
TS28: periolivary nucleus	Weak
TS28: supramammillary nucleus	Weak
TS28: ventral tegmental area	Weak
TS28: caudate-putamen	Trace	Single cells
TS28: accumbens nucleus	Absent
TS28: anterior commissure	Absent
TS28: nucleus reuniens	Absent
TS28: olfactory tubercle	Absent

Specimen 4A: postnatal adult (more

)

Structure	Level	Image
TS28: main olfactory bulb glomerular layer	Present	4A
TS28: main olfactory bulb mitral cell layer	Present	4A
TS28: main olfactory bulb granule cell layer	Weak	4A

Specimen 4B: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: medial septal nucleus	Present		4B

Specimen 4C: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus CA3	Strong	Regionally restricted	4C	Strong in the pyramidal layer, weak in other regions.
TS28: hippocampus CA1	Strong	Regionally restricted	4C	Strong in the stratum oriens, weak in other regions.
TS28: hippocampus CA2	Weak		4C

Specimen 4D: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus CA3	Strong	Regionally restricted	4D	Strong in the pyramidal layer, weak in other regions.
TS28: hippocampus CA1	Strong	Regionally restricted	4D	Strong in the stratum oriens, weak in other regions.
TS28: hippocampus CA2	Weak		4D

Specimen 4E: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: piriform cortex	Very strong		4E

Specimen 4F: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: paraventricular hypothalamic nucleus	Very strong		4F
TS28: ventromedial hypothalamic nucleus	Very strong		4F

Specimen 4G: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: amygdala	Very strong		4G
TS28: piriform cortex	Very strong		4G

Specimen 4H: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: subiculum	Very strong		4H

Specimen 5A: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel endothelium	Present	Regionally restricted	5A	Expression is in brain capillary endothelial cells.

Specimen 5C: postnatal adult (more

)

Structure	Level	Image
TS28: retina ganglion cell layer	Present	5C
TS28: retina inner nuclear layer	Present	5C
TS28: retina outer nuclear layer	Present	5C

Specimen 5D: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present		5D
TS28: deep cerebellar nucleus	Present		5D

Specimen 5E: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cortical layer V	Very strong		5E
TS28: cerebral cortex	Present		5E

Specimen 5F: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cortical layer V	Very strong		5F
TS28: cerebral cortex	Present		5F

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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