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Gene Expression Data
Assay Details
Assay
Reference: J:162757 Kawamura N, et al., Optic Nerve Compression and Retinal Degeneration in Tcirg1 Mutant Mice Lacking the Vacuolar-Type H-ATPase a3 Subunit. PLoS One. 2010;5(8):e12086
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4819865
Gene symbol: Tcirg1
Gene name: T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
Antibody: Anti-a3
Detection system: Secondary antibody
Results
Specimen 5A: postnatal day 15 (more )
Note: Embedded in methacrylate.
Structure Level Pattern Image Note
TS28: photoreceptor layer Absent 5A
TS28: pigmented retinal epithelium Absent 5A
TS28: choroidal vasculature Present Regionally restricted 5A Expression was highly expressed in the choriocapillary meshwork.
Specimen 5B & 5C: postnatal day 15 (more )
Note: Fig. 5C shows staining for nuclei. Embedded in methacrylate.
Structure Level Pattern Image Note
TS28: choroidal vasculature Present Regionally restricted 5B , 5C Expression was highly expressed in the choriocapillary meshwork.
TS28: photoreceptor layer Absent 5B , 5C
TS28: pigmented retinal epithelium Absent 5B , 5C
Specimen 6A: postnatal day 15 (more )
Note: Embedded in methacrylate.
Structure Level Pattern Image Note
TS28: choroidal vasculature Present 6A
Specimen 6C & 6D: postnatal day 15 (more )
Note: Fig. 6D shows staining for nuclei. Embedded in methacrylate.
Structure Level Pattern Image Note
TS28: ciliary body Weak 6D , 6C
TS28: choroidal vasculature Present 6D , 6C
Specimen 7A & 7C: postnatal day 15 (more )
Note: Double labeled: red - Tcirg1; green - Pecam1 (assay MGI:4819949). Embedded in methacrylate.
Structure Level Pattern Image Note
TS28: ciliary body Present 7C , 7A
Specimen 7D & 7F: postnatal day 15 (more )
Note: Double labeled: red - Tcirg1; green - Pecam1 (assay MGI:4819949). Embedded in methacrylate.
Structure Level Pattern Image Note
TS28: choroidal vasculature Present 7F , 7D Expression was detected in the choriocapillary meshwork.
Specimen 8A: postnatal day 15 (more )
Note: Embedded in methacrylate.
Structure Level Pattern Image Note
TS28: optic choroid Present 8A
Specimen 8B: postnatal day 15; Tcirg1tm1.2Ywd/Tcirg1tm1.2Ywd (more )
Note: Embedded in methacrylate.
Structure Level Pattern Image Note
TS28: optic choroid Absent 8B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory