About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:102843 Zhang Z, et al., Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development. Development. 2005 Dec;132(23):5307-15
Assay type: Recombinase reporter
MGI Accession ID: MGI:4819502
Gene symbol: Nkx2-5
Gene name: NK2 homeobox 5
Reporter: lacZ
Direct Detection
Results
Specimen Fig. 2B: embryonic day 10.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: trunk Present 2B

Specimen Fig. 2Ba: embryonic day 10.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Sagittal section through the embryo.
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 2Ba Staining is observed in the core mesoderm of pharyngeal arches I-III.
TS17: 2nd branchial arch Present 2Ba Staining is observed in the core mesoderm of pharyngeal arches I-III.
TS17: 3rd branchial arch Present 2Ba Staining is observed in the core mesoderm of pharyngeal arches I-III.

Specimen Fig. 2Bb: embryonic day 10.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Sagittal section through the embryo.
Structure Level Pattern Image Note
TS17: outflow tract Present 2Bb
TS17: heart Present 2Bb Staining is observed in the secondary heart field.

Specimen Fig. 2Bc: embryonic day 10.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Sagittal section through the embryo.
Structure Level Pattern Image Note
TS17: 3rd branchial pouch Present 2Bc
TS17: 4th branchial pouch Present 2Bc
TS17: branchial arch endoderm Present 2Bc

Specimen Fig. 3B: embryonic day 9.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: trunk Present 3B

Specimen Fig. 3B': embryonic day 9.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Coronal section through pharynx.
Structure Level Pattern Image Note
TS14: branchial arch ectoderm Present Patchy 3B'' , 3B'
TS14: branchial arch endoderm Present Patchy 3B'' , 3B'


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory