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Gene Expression Data
Assay Details
Assay
Reference: J:103820 Reiter JF, et al., Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 1;20(1):22-7
Assay type: RNA in situ
MGI Accession ID: MGI:4461973
Gene symbol: Gli1
Gene name: GLI-Kruppel family member GLI1
Results
Specimen 2F left: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present 2F left

Specimen 2F right: embryonic day 9.5; Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Structure Level Pattern Image Note
TS15: embryo Weak 2F right Expression was broadly diminished in the mutant embryo.

Specimen 2G left: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present 2G left

Specimen 2G right: embryonic day 10.5; Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Structure Level Pattern Image Note
TS17: neural tube Weak 2G right

Specimen 3G wild type: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Present Graded 3G wild type Expression was detected in a dorsoventral gradient.

Specimen 3G Ptch-/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3G Ptch-/- Expression was widely up-regulated and ectopically located in the dorsal neural tube.

Specimen 3G Tectonic-/- Ptch-/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps, Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Structure Level Pattern Image Note
TS15: neural tube Weak Regionally restricted 3G Tectonic-/- Ptch-/- Expression was detected at a uniform low level throughout the dorsoventral extent of the neural tube.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory