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Gene Expression Data
Assay Details
Assay
Reference: J:108509 Blaess S, et al., Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region. Development. 2006 May;133(9):1799-809
Assay type: RNA in situ
MGI Accession ID: MGI:3810941
Gene symbol: Spry1
Gene name: sprouty RTK signaling antagonist 1
Probe: Sprouty1 probe
Probe preparation: Antisense RNA
Results
Specimen 6C: embryonic day 10.5 (more )
Note: This is a midline section.
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 6C
TS17: rhombomere 1 Present Regionally restricted 6C Expression is present in the anterior part.
Specimen 6D: embryonic day 10.5; Smotm2Amc/Smotm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. This is a midline section.
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present Regionally restricted 6D The expression domain is severely reduced in the mutant compared to wild type.
TS17: rhombomere 1 Present Regionally restricted 6D The expression domain is severely reduced in the mutant compared to wild type.
Specimen 6I: embryonic day 12.5 (more )
Note: This is a midline section.
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present 6I
Specimen 6J: embryonic day 12.5; Smotm1Amc/Smotm2Amc, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. This is a midline section.
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present 6J A slight reduction in the expression domain was observed.
Specimen Not shown: embryonic day 12.5; Gli2tm6Alj/Gli2tm6Alj, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present Expression is the same as in wild type.
Specimen Not shown: embryonic day 12.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present Expression is the same as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory