Gene Expression Data
Assay Details
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Assay
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Reference:
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J:61521
Houzelstein D, et al., The expression of the homeobox gene Msx1 reveals two populations of dermal progenitor cells originating from the somites. Development. 2000 May;127(10):2155-64
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:3799732
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Gene symbol:
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Msx1
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Gene name:
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msh homeobox 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1A:
embryonic day 11.0; Msx1tm1Bero/Msx1 +
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 11.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: trunk mesenchyme |
Present |
Regionally restricted |
1A
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Expression was detected in the dorsal mesenchyme in the back of the trunk. The signal was seen on either side of the neural tube, exhibits a segmental pattern, and extends over 15-20 segments from the first cervical vertebra to the level of the hindlimb.
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| TS18: neural tube |
Strong |
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1A
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Specimen
1C:
embryonic day 13.0; Msx1tm1Bero/Msx1 +
(more )
Specimen
1C:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: trunk mesenchyme |
Present |
Regionally restricted |
1C
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Expression was detected in the dorsal mesenchyme. Expression was most pronounced at the level of the forelimbs.
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Specimen
1D:
embryonic day 14.0; Msx1tm1Bero/Msx1 +
(more )
Specimen
1D:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 14.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: trunk mesenchyme |
Present |
Regionally restricted |
1D
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Expression was still detectable at the level of the forelimbs.
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Specimen
2A:
embryonic day 12.0; Msx1tm1Bero/Msx1 +
(more )
Specimen
2A:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: trunk mesenchyme |
Present |
Regionally restricted |
2A
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Expression was detected in stripes corresponding to one vertebral condensation.
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Specimen
2B:
embryonic day 13.0; Msx1tm1Bero/Msx1 +
(more )
Specimen
2B:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: trunk mesenchyme |
Present |
Regionally restricted |
2B
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Positive cells form stripes in phase with the somite.
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Specimen
3A & 3B:
embryonic day 14.0; Msx1tm1Bero/Msx1 +
(more )
Note: Fig. 3B is a higher magnification of the boxed area in Fig. 3A.
Specimen
3A & 3B:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 14.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Fig. 3B is a higher magnification of the boxed area in Fig. 3A.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: trunk mesenchyme |
Present |
Regionally restricted |
3B
,
3A
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Expression was detected in a few cells deep in the dorsal mesenchyme. Expression was restricted to a narrow region just above the central part of the neural tube.
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Specimen
7A:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL * C57BL/6J
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
Pax3Sp/Pax3Sp
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Age:
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embryonic day 11.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: trunk mesenchyme |
Present |
Regionally restricted |
7A
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Expression was found in dorsal mesenchyme as in wild type embryos.
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Specimen
7B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL * C57BL/6J
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
Pax3Sp/Pax3Sp
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: trunk mesenchyme |
Present |
Regionally restricted |
7B
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Expression was found in dorsal mesenchyme as in wild type embryos.
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Specimen
8A:
embryonic day 11.0; Msx1tm1Bero/Msx1 +
(more )
Specimen
8A:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 11.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: trunk mesenchyme |
Present |
Regionally restricted |
8A
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Expression was detected in the dorsal mesenchyme overlying the neural tube and extending laterally to the most medial region of the somite.
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Specimen
8C:
embryonic day 12.0; Msx1tm1Bero/Msx1 +
(more )
Specimen
8C:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: trunk mesenchyme |
Present |
Regionally restricted |
8C
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Expression was detected in dorsal mesenchyme. In the lateral part of the expression domain, expression was deeper in the mesenchyme at E12 than at E11.
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Specimen
8E:
embryonic day 13.0; Msx1tm1Bero/Msx1 +
(more )
Specimen
8E:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1+
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: trunk mesenchyme |
Present |
Regionally restricted |
8E
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Expression was detected deeper in the mesenchymal cell layer.
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