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Gene Expression Data
Assay Details
Assay
Reference: J:134680 Garcia-Frigola C, et al., Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms. Development. 2008 May;135(10):1833-41
Assay type: RNA in situ
MGI Accession ID: MGI:3795524
Gene symbol: Ephb1
Gene name: Eph receptor B1
Probe: EphB1 cDNA3
Visualized with: Fluorescein
Results
Specimen 3Bb,b': embryonic day 15.5 (more )
Note: Double labeled: green - Ephb1; red - Zic2 (assay MGI:3795523).
Structure Level Pattern Image Note
TS23: neural retina Present Regionally restricted 3B c' , 3B b , 3B b' , 3B c Expression in retinal ganglion cells (RGCs) located more centrally in the neural retina.

Specimen 4Aa': embryonic day 16.5 (more )
Note: Double labeled: green - Ephb1; red - Zic2 (assay MGI:3795523).
Structure Level Pattern Image Note
TS24: neural retina Present Regionally restricted 4Aa'' , 4Aa' Expression in the ventrotemporal (VT) retina, in the same area as Zic2.

Specimen 4Ab': embryonic day 16.5; Zic2tm1Jaru/Zic2+ (more )
Note: Double labeled: green - Ephb1; red - Zic2 (assay MGI:3795523).
Structure Level Pattern Image Note
TS24: neural retina Weak Regionally restricted 4Ab' , 4Ab'' Expression is reduced compared with the wild type.

Specimen 4Ac': embryonic day 16.5; Zic2tm1Jaru/Zic2tm1Jaru (more )
Note: Double labeled: green - Ephb1; red - Zic2 (assay MGI:3795523).
Structure Level Pattern Image Note
TS24: neural retina Absent 4Ac'' , 4Ac'

Specimen 4Ba: embryonic day 17.5 (more )
Note: Double labeled: green - Ephb1; red - Zic2 (assay MGI:3795523).
Structure Level Pattern Image Note
TS25: brain Present Regionally restricted 4Ba Extensive expression in the brain.
TS25: telencephalon Present Regionally restricted 4Ba Authors report expression in the entorhinal cortex, hippocampus and lateral globus pallidus.

Specimen 4Bb: embryonic day 17.5; Zic2tm1Jaru/Zic2tm1Jaru (more )
Note: Double labeled: green - Ephb1; red - Zic2 (assay MGI:3795523).
Structure Level Pattern Image Note
TS25: brain Present Regionally restricted 4Bb Extensive expression in the brain in a pattern very similar to that of wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory