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Gene Expression Data
Assay Details
Assay
Reference: J:21262 Wilkinson DG, et al., Expression pattern of the mouse T gene and its role in mesoderm formation [see comments]. Nature. 1990 Feb 15;343(6259):657-9
Assay type: RNA in situ
MGI Accession ID: MGI:3775478
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Probe: T cDNA4
Probe preparation: labelled with S35 RNA
Results
Specimen 2a,b: embryonic day 7.0 (more )
Structure Level Pattern Image Note
TS10: embryo mesoderm Present Regionally restricted 2a/b Expression in mesoderm cells next to the primitive streak, but not in more lateral mesoderm.
TS10: embryo ectoderm Present Regionally restricted 2a/b Expression in primitive ectoderm next to the primitive streak, consisting of epithelial cells destined to delaminate and form mesoderm and definitive endoderm.
TS10: definitive endoderm Present 2a/b Expression in primitive ectoderm next to the primitive streak, consisting of epithelial cells destined to delaminate and form mesoderm and definitive endoderm.
Specimen 2c,d: embryonic day 7.0 (more )
Structure Level Pattern Image Note
TS10: embryo mesoderm Present Regionally restricted 2c/d Expression in mesoderm cells next to the primitive streak, but not in more lateral mesoderm.
TS10: embryo ectoderm Present Regionally restricted 2c/d Expression in primitive ectoderm next to the primitive streak, consisting of epithelial cells destined to delaminate and form mesoderm and definitive endoderm.
TS10: definitive endoderm Present 2c/d Expression in primitive ectoderm next to the primitive streak, consisting of epithelial cells destined to delaminate and form mesoderm and definitive endoderm.
Specimen 2e,f: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo ectoderm Present Regionally restricted 2e/f Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS13: embryo mesenchyme Present Regionally restricted 2e/f Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS13: allantois Absent 2e/f No expression in allantois or other extraembryonic mesodermal tissues.
TS13: extraembryonic mesenchyme Absent 2e/f No expression in allantois or other extraembryonic mesodermal tissues.
TS13: notochordal plate Present 2e/f
Specimen 2g,h: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo ectoderm Present Regionally restricted 2g/h Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS13: embryo mesenchyme Present Regionally restricted 2g/h Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS13: allantois Absent 2g/h No expression in allantois or other extraembryonic mesodermal tissues.
TS13: extraembryonic mesenchyme Absent 2g/h No expression in allantois or other extraembryonic mesodermal tissues.
TS13: notochordal plate Present 2g/h
Specimen 2i,j: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo ectoderm Present Regionally restricted 2i/j Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS13: embryo mesenchyme Present Regionally restricted 2i/j Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS13: allantois Absent 2i/j No expression in allantois or other extraembryonic mesodermal tissues.
TS13: extraembryonic mesenchyme Absent 2i/j No expression in allantois or other extraembryonic mesodermal tissues.
TS13: paraxial mesenchyme Absent 2i/j
Specimen 2k,l: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo ectoderm Present Regionally restricted 2k/l Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS13: embryo mesenchyme Present Regionally restricted 2k/l Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS13: allantois Absent 2k/l No expression in allantois or other extraembryonic mesodermal tissues.
TS13: extraembryonic mesenchyme Absent 2k/l No expression in allantois or other extraembryonic mesodermal tissues.
TS13: notochordal plate Present 2k/l
Specimen E8.5 not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Absent Expression down-regulated to undetectable levels in lateral mesoderm.
Specimen E9.5 not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo ectoderm Present Regionally restricted Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
TS15: embryo mesenchyme Present Regionally restricted Pattern of expression in early mesoderm and primitive ectoderm next to the primitive streak, similar to that seen at E7.
Specimen 2m,n: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: notochord Present 2m/n
Specimen 2o,p: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: trunk mesenchyme Present Regionally restricted 2o/p Expression in repeated clusters of cells along the length of the spinal cord.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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