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Gene Expression Data
Assay Details
Assay
Reference: J:128545 Visel A, et al., Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain. J Comp Neurol. 2006 Jun 10;496(5):684-97
Assay type: RNA in situ
MGI Accession ID: MGI:3768401
Gene symbol: Adcy8
Gene name: adenylate cyclase 8
Probe: MH854 probe 828
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: A dual signal amplification strategy, termed catalyzed reporter deposition (CARD), was used for detection.
Results
Specimen Table 2-P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Strong HB464
TS28: main olfactory bulb external plexiform layer Absent HB464
TS28: main olfactory bulb mitral cell layer Strong HB464
TS28: main olfactory bulb internal plexiform layer Absent HB464
TS28: main olfactory bulb granule cell layer Absent HB464
TS28: cerebral cortex Moderate HB464
TS28: hippocampus CA1 Moderate HB464
TS28: hippocampus CA2 Absent HB464
TS28: hippocampus CA3 Absent HB464
TS28: dentate gyrus Absent HB464
TS28: corpus striatum Absent HB464
TS28: telencephalon septum Absent HB464
TS28: amygdala Weak HB464
TS28: thalamus Moderate HB464
TS28: hypothalamus Weak HB464
TS28: pretectum Weak HB464
TS28: superior colliculus Weak HB464
TS28: inferior colliculus Absent HB464
TS28: midbrain tegmentum Weak HB464
TS28: cerebellum molecular layer Absent HB464
TS28: cerebellum Purkinje cell layer Absent HB464
TS28: cerebellum granule cell layer Absent HB464
TS28: pons Weak HB464
TS28: medulla oblongata Weak HB464
Specimen Table 2-P56: postnatal day 56 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Strong BA106 , HB462
TS28: main olfactory bulb external plexiform layer Absent BA106 , HB462
TS28: main olfactory bulb mitral cell layer Strong BA106 , HB462
TS28: main olfactory bulb internal plexiform layer Absent BA106 , HB462
TS28: main olfactory bulb granule cell layer Absent BA106 , HB462
TS28: cerebral cortex Weak HB462 , BA106
TS28: hippocampus CA1 Moderate BA106 , HB462
TS28: hippocampus CA2 Absent HB462 , BA106
TS28: hippocampus CA3 Absent BA106 , HB462
TS28: dentate gyrus Absent HB462 , BA106
TS28: corpus striatum Absent HB462 , BA106
TS28: telencephalon septum Absent BA106 , HB462
TS28: amygdala Weak BA106 , HB462
TS28: thalamus Moderate HB462 , BA106
TS28: hypothalamus Weak HB462 , BA106
TS28: pretectum Absent HB462 , BA106
TS28: superior colliculus Weak HB462 , BA106
TS28: inferior colliculus Absent HB462 , BA106
TS28: midbrain tegmentum Weak HB462 , BA106
TS28: cerebellum molecular layer Absent HB462 , BA106
TS28: cerebellum Purkinje cell layer Absent BA106 , HB462
TS28: cerebellum granule cell layer Weak BA106 , HB462
TS28: pons Weak BA106 , HB462
TS28: medulla oblongata Weak HB462 , BA106
Specimen 1E: postnatal day 56 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Strong 1E
TS28: main olfactory bulb mitral cell layer Strong 1E
Specimen 1I: embryonic day 14.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS22: main olfactory bulb Present Regionally restricted 1I Expression is restricted to the mantle layer.
Specimen 2F: postnatal day 56 (more )
Note: This is a coronal section.
Structure Level Pattern Image Note
TS28: cortical layer V Present 2F This is the layer with the highest expression level.
TS28: cortical layer II Weak Single cells 2F There is a small number of weakly expressing cells.
TS28: cortical layer III Weak Single cells 2F There is a small number of weakly expressing cells.
Specimen 2H: embryonic day 14.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 2H Expression is present in the rostralmost cortex in scattered cells that are grouped around the base of the nascent olfactory bulb.
Specimen 3K: postnatal day 7 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 3K
TS28: hippocampus CA2 Absent 3K
TS28: hippocampus CA3 Absent 3K
Specimen 3L: postnatal day 56 (more )
Note: This is a coronal section.
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 3L
TS28: hippocampus CA2 Absent 3L
TS28: hippocampus CA3 Absent 3L
Specimen 5E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: thalamus Present Regionally restricted 5E Expression is sharply restricted to a dorsal subregion of the dorsal thalamus.
Specimen 5F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: thalamus Present Regionally restricted 5F Expression is sharply restricted to a dorsal subregion of the dorsal thalamus.
Specimen 6B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midbrain lateral wall Present Regionally restricted 6B Expression is present in the ventral part of the mantle layer of the midbrain roof plate. It is also expressed in more lateral parts of the mantle layer in a subset of cells.
TS22: midbrain ventricular layer Absent 6B There is no expression in the neuroepithelium.
Specimen 6E: embryonic day 14.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS22: midbrain lateral wall Present Regionally restricted 6E Expression is present along the full length of the midbrain roof with no obvious restrocaudal gradient.
Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: stomach Present Regionally restricted Expression is present in some regions of the stomach mucosa.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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