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Gene Expression Data
Assay Details
Assay
Reference: J:128545 Visel A, et al., Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain. J Comp Neurol. 2006 Jun 10;496(5):684-97
Assay type: RNA in situ
MGI Accession ID: MGI:3768398
Gene symbol: Adcy5
Gene name: adenylate cyclase 5
Probe: HB461 probe 160
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: A dual signal amplification strategy, termed catalyzed reporter deposition (CARD), was used for detection. It is possible another probe (MGI:3724645) was used in this assay.
Results
Specimen Table 2-P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Moderate HB461
TS28: main olfactory bulb external plexiform layer Absent HB461
TS28: main olfactory bulb mitral cell layer Strong HB461
TS28: main olfactory bulb internal plexiform layer Absent HB461
TS28: main olfactory bulb granule cell layer Absent HB461
TS28: cerebral cortex Weak HB461
TS28: hippocampus CA1 Moderate HB461
TS28: hippocampus CA2 Moderate HB461
TS28: hippocampus CA3 Weak HB461
TS28: dentate gyrus Weak HB461
TS28: corpus striatum Strong HB461
TS28: telencephalon septum Moderate HB461
TS28: amygdala Moderate HB461
TS28: thalamus Moderate HB461
TS28: hypothalamus Weak HB461
TS28: pretectum Weak HB461
TS28: superior colliculus Weak HB461
TS28: inferior colliculus Weak HB461
TS28: midbrain tegmentum Weak HB461
TS28: cerebellum molecular layer Absent HB461
TS28: cerebellum Purkinje cell layer Absent HB461
TS28: cerebellum granule cell layer Weak HB461
TS28: pons Weak HB461
TS28: medulla oblongata Weak HB461
Specimen Table 2-P56: postnatal day 56 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Moderate BA103 , HB459
TS28: main olfactory bulb external plexiform layer Absent BA103 , HB459
TS28: main olfactory bulb mitral cell layer Strong HB459 , BA103
TS28: main olfactory bulb internal plexiform layer Absent BA103 , HB459
TS28: main olfactory bulb granule cell layer Absent BA103 , HB459
TS28: cerebral cortex Weak HB459 , BA103
TS28: hippocampus CA1 Weak HB459 , BA103
TS28: hippocampus CA2 Strong HB459 , BA103
TS28: hippocampus CA3 Weak HB459 , BA103
TS28: dentate gyrus Weak HB459 , BA103
TS28: corpus striatum Strong BA103 , HB459
TS28: telencephalon septum Moderate HB459 , BA103
TS28: amygdala Weak BA103 , HB459
TS28: thalamus Weak BA103 , HB459
TS28: hypothalamus Moderate HB459 , BA103
TS28: pretectum Absent HB459 , BA103
TS28: superior colliculus Weak BA103 , HB459
TS28: inferior colliculus Weak BA103 , HB459
TS28: midbrain tegmentum Moderate HB459 , BA103
TS28: cerebellum molecular layer Absent HB459 , BA103
TS28: cerebellum Purkinje cell layer Absent HB459 , BA103
TS28: cerebellum granule cell layer Absent HB459 , BA103
TS28: pons Weak BA103 , HB459
TS28: medulla oblongata Weak BA103 , HB459
Specimen 1C: postnatal day 56 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Strong 1C
TS28: main olfactory bulb mitral cell layer Strong 1C
Specimen 1H: embryonic day 14.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS22: main olfactory bulb Present Regionally restricted 1H Expression is restricted to the mantle layer.
Specimen 2D: postnatal day 56 (more )
Note: This is a coronal section.
Structure Level Pattern Image Note
TS28: cortical layer II Present 2D Expression is present in layers 2/3. This is one of layers with the highest expression levels.
TS28: cortical layer III Present 2D Expression is present in layers 2/3. This is one of layers with the highest expression levels.
TS28: cortical layer V Present 2D This is one of layers with the highest expression levels.
Specimen 2K: embryonic day 14.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS22: cerebral cortex Strong Regionally restricted 2K There is strong expression in the preplate.
Specimen 3E: postnatal day 7 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: hippocampus Present Uniform 3E Expression is rather uniform.
Specimen 3F: postnatal day 56 (more )
Note: This is a coronal section.
Structure Level Pattern Image Note
TS28: hippocampus CA2 Strong 3F
Specimen 3P: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hippocampus Present Regionally restricted 3P Expression is present in the marginal zone.
Specimen 4C: postnatal day 7 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: corpus striatum Strong Non-Uniform 4C Expression is present in a large fraction of cells in the striatum.
TS28: accumbens nucleus Present 4C Expression is prominent.
TS28: caudate-putamen Present 4C Expression is prominent.
TS28: globus pallidus Present 4C Expression is much weaker than that seen in the caudate putamen and nucleus accumbens.
Specimen 4F: postnatal day 56 (more )
Note: This is a coronal section in the anterior striatum.
Structure Level Pattern Image Note
TS28: corpus striatum Strong Non-Uniform 4I , 4F Expression is present in a large fraction of cells in the striatum.
TS28: accumbens nucleus Present 4F Expression is prominent.
TS28: caudate-putamen Present 4F Expression is prominent.
TS28: globus pallidus Present 4F Expression is much weaker than that seen in the caudate putamen and nucleus accumbens.
Specimen 4L: postnatal day 56 (more )
Note: This is a coronal section from a more posterior region of the striatum.
Structure Level Pattern Image Note
TS28: corpus striatum Strong Non-Uniform 4L Expression is present in a large fraction of cells in the striatum.
TS28: accumbens nucleus Present 4L Expression is prominent.
TS28: caudate-putamen Present 4L Expression is prominent.
TS28: globus pallidus Present 4L Expression is much weaker than that seen in the caudate putamen and nucleus accumbens.
Specimen 6C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tectum Present Regionally restricted 6C Expression is present in the developing tectum at the midline, as well as in more lateral sections. It is found predominantly in the mantle layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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