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Gene Expression Data
Assay Details
Assay
Reference: J:118222 Vauti F, et al., The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour. Gene. 2007 Mar 15;389(2):174-85
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3707512
Gene symbol: Trmt1l
Gene name: tRNA methyltransferase 1 like
Reporter: lacZ
Direct Detection
Assay notes: Specimens were fixed in 2% paraformaldehyde and 0.25% glutaraldehyde.
Results
Specimen 4A: embryonic day 10.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS18: heart Present 4A
Specimen 4B: embryonic day 11.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS19: heart Present 4B
Specimen 4C: embryonic day 12.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS20: choroid plexus Strong 4C
TS20: spinal ganglion Strong 4C
TS20: trigeminal ganglion Strong 4C
Specimen 4D: embryonic day 12.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Strong 4D
TS20: trigeminal nerve Strong 4D
Specimen 4E: embryonic day 13.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS21: choroid plexus Strong 4E
TS21: spinal ganglion Strong 4E
Specimen 4F: embryonic day 14.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS22: heart Strong 4F
TS22: spinal ganglion Strong 4F
TS22: trigeminal ganglion Strong 4F
TS22: facial ganglion Present 4F Expression in the nucleus facialis.
Specimen 4G: embryonic day 15.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS23: olfactory epithelium Present 4G
TS23: choroid plexus Strong 4G
TS23: heart Strong 4G
TS23: spinal ganglion Strong 4G
TS23: trigeminal ganglion Strong 4G
Specimen 4H: embryonic day 16.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS24: choroid plexus Present 4H
TS24: heart Present 4H
TS24: olfactory epithelium Present 4H
TS24: brown fat Present 4H
Specimen 4I: embryonic day 16.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS24: choroid plexus Present 4I
TS24: olfactory epithelium Present 4I
TS24: nasopharynx Present 4I Expression in the nasopharyngeal tract.
TS24: epiglottis Present 4I
TS24: esophagus Present 4I
TS24: medulla oblongata Present 4I
TS24: midbrain Present 4I
TS24: thalamus Present 4I
TS24: brain ventricular layer Present 4I Expression in the ependyma.
TS24: spinal cord meninges Present 4I
Specimen 4J: embryonic day 16.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS24: heart Present 4J
TS24: lung Present 4J
TS24: axial skeleton Present 4J Expression in the vertebral column.
TS24: intervertebral disc Present 4J
TS24: spinal cord Present 4J
Specimen 4K: embryonic day 18.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS26: bronchus epithelium Present 4K Expression in the bronchial epithelium.
Specimen 5A E18.5: embryonic day 18.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS26: main olfactory bulb Present 5A E18.5
TS26: cerebral cortex Present 5A E18.5 Expression in the neocortex.
TS26: medulla oblongata Present 5A E18.5
TS26: midbrain Present 5A E18.5
TS26: thalamus Present 5A E18.5
TS26: cerebellum Present Regionally restricted 5A E18.5 No expression in the cerebellum white matter.
Specimen 5A P4: postnatal day 4; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 5A P4
TS28: cerebral cortex Present 5A P4 Expression in the neocortex.
TS28: thalamus Present 5A P4
TS28: abducens nucleus Present 5A P4
TS28: dorsal motor nucleus of vagus nerve Present 5A P4
TS28: facial nucleus Present 5A P4
TS28: hypoglossal nucleus Present 5A P4
TS28: oculomotor nucleus Present 5A P4
TS28: red nucleus Present 5A P4
TS28: trigeminal nucleus Present 5A P4
TS28: brain ependyma Present 5A P4
TS28: cerebral aqueduct Present 5A P4
TS28: choroid plexus Present 5A P4
TS28: cerebellum Present Regionally restricted 5A P4
TS28: cerebellum white matter Absent 5A P4
Specimen 5A P20: postnatal day 20; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 5A P20
TS28: cerebral cortex Present 5A P20 Expression in the neocortex.
TS28: corpus striatum Present 5A P20
TS28: medulla oblongata Present 5A P20
TS28: midbrain Present 5A P20
TS28: thalamus Present 5A P20
TS28: cerebellum Present Regionally restricted 5A P20
TS28: cerebellum white matter Absent 5A P20
Specimen 5A adult: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 5A adult
TS28: cerebral cortex Present 5A adult Expression in the neocortex.
TS28: corpus striatum Present 5A adult
TS28: medulla oblongata Present 5A adult
TS28: midbrain Present 5A adult
TS28: thalamus Present 5A adult
TS28: cerebellum Present Regionally restricted 5A adult
TS28: cerebellum white matter Absent 5A adult
Specimen 5B E18.5: embryonic day 18.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS26: brain Present Regionally restricted 5B E18.5
Specimen 5B adult: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS28: brain Strong Regionally restricted 5B adult
Specimen 5C adult: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebral internal capsule Present 5C adult
TS28: corpus callosum Present 5C adult
TS28: fornix Present 5C adult
TS28: cerebral hemisphere white matter Present Regionally restricted 5C adult Expression in the external capsule and stria terminalis.
TS28: cerebellum Present Regionally restricted 5C adult
TS28: hippocampus Present Regionally restricted 5C adult Expression in the hippocampal fissure.
TS28: cerebellum white matter Absent 5C adult
Specimen 6A: postnatal day 4; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb external plexiform layer Present 6A
TS28: main olfactory bulb glomerular layer Present 6A
TS28: main olfactory bulb mitral cell layer Present 6A
Specimen 6B: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb external plexiform layer Present 6B
TS28: main olfactory bulb glomerular layer Present 6B
TS28: main olfactory bulb mitral cell layer Strong 6B
TS28: main olfactory bulb granule cell layer Weak 6B
TS28: main olfactory bulb internal plexiform layer Weak 6B
Specimen 6C: postnatal day 13; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cortical layer IV Present 6C
TS28: cortical layer V Present 6C
Specimen 6D: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: neocortex layer Present 6D Expression in all neocortical layers.
Specimen 6E: postnatal day 5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 6E Expression in the neocortex.
TS28: thalamus Present 6E
TS28: corpus striatum Weak 6E
Specimen 6F: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebral cortex Strong 6F Expression in the neocortex.
TS28: corpus striatum Strong 6F
Specimen 6G: postnatal day 20; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6G
TS28: cerebellum granule cell layer Present 6G
TS28: cerebellum molecular layer Present 6G
TS28: cerebellum white matter Absent 6G
Specimen 6H: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 6H
TS28: cerebellum white matter Absent 6H
Specimen 6I: postnatal day 2; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS27: brain ependyma Present 6I
TS27: hippocampus pyramidal cell layer Present 6I
Specimen 6J: postnatal day 13; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Present 6J
TS28: hippocampus molecular layer Present 6J Expression in the lacunosum moleculare.
Specimen 6K: postnatal day 20; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: dentate gyrus polymorphic layer Present 6K
TS28: hippocampus pyramidal cell layer Present 6K
TS28: dentate gyrus molecular layer Present Regionally restricted 6K Expression in parts of the molecular layer.
Specimen 6L: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Present 6L
TS28: hippocampus molecular layer Present 6L Expression in the lacunosum moleculare.
TS28: dentate gyrus polymorphic layer Present 6L
TS28: hippocampus stratum radiatum Present 6L
TS28: dentate gyrus molecular layer Present Regionally restricted 6L Expression in parts of the molecular layer.
TS28: hippocampus stratum lucidum Present Single cells 6L
TS28: hippocampus stratum oriens Present Single cells 6L
TS28: hippocampus Present Regionally restricted 6L
TS28: dentate gyrus granule cell layer Absent 6L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory