Synm Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:92830 Xue ZG, et al., The mouse synemin gene encodes three intermediate filament proteins generated by alternative exon usage and different open reading frames. Exp Cell Res. 2004 Aug 15;298(2):431-44
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:3693643
Gene symbol:	Synm
Gene name:	synemin, intermediate filament protein

Antibody:	anti-Syn3
Detection system:	Secondary antibody coupled to fluorescein
Assay notes:	The antibody used in this assay recognizes the H/M isoform.

Results

Specimen 6A: postnatal (more

)

Structure	Level	Pattern	Image	Note
TS28: detrusor muscle of bladder	Present		6A

Specimen 6B: postnatal; Des^tm1Cba/Des^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: detrusor muscle of bladder	Present		6B	Expression levels in the mutant are the same as in wild-type animals.

Specimen 6C: postnatal; Vim^tm1Cba/Vim^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: detrusor muscle of bladder	Present		6C	Expression levels are lower in the mutant than in wild-type animals.

Specimen 6D: postnatal; Des^tm1Cba/Des^tm1Cba, Vim^tm1Cba/Vim^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: detrusor muscle of bladder	Present		6D	Expression levels are much lower in the mutant than in wild-type animals.

Specimen 6E: postnatal (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel smooth muscle	Present		6E

Specimen 6F: postnatal; Des^tm1Cba/Des^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel smooth muscle	Present		6F	Expression levels in the mutant are the same as in wild-type animals.

Specimen 6G: postnatal; Vim^tm1Cba/Vim^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel smooth muscle	Present		6G	Expression levels are lower in the mutant than in wild-type animals.

Specimen 6H: postnatal; Des^tm1Cba/Des^tm1Cba, Vim^tm1Cba/Vim^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel smooth muscle	Absent		6H

Specimen 6I: postnatal (more

)

Structure	Level	Pattern	Image	Note
TS28: skeletal muscle	Present		6I

Specimen 6J: postnatal; Des^tm1Cba/Des^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: skeletal muscle	Absent		6J	There was no labeling of Z bands.

Specimen 6K: postnatal; Vim^tm1Cba/Vim^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: skeletal muscle	Present		6K	Expression levels in the mutant are the same as in wild-type animals.

Specimen 6L: postnatal; Des^tm1Cba/Des^tm1Cba, Vim^tm1Cba/Vim^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: skeletal muscle	Absent		6L

Specimen 6M: postnatal (more

)

Structure	Level	Pattern	Image	Note
TS28: cardiac muscle tissue	Present		6M

Specimen 6N: postnatal; Des^tm1Cba/Des^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: cardiac muscle tissue	Absent		6N	There was no labeling of Z bands.

Specimen 6O: postnatal; Vim^tm1Cba/Vim^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: cardiac muscle tissue	Present		6O	Expression levels in the mutant are the same as in wild-type animals.

Specimen 6P: postnatal; Des^tm1Cba/Des^tm1Cba, Vim^tm1Cba/Vim^tm1Cba (more

)

Structure	Level	Pattern	Image	Note
TS28: cardiac muscle tissue	Absent		6P

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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