Gene Expression Data
Assay Details
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Assay
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Reference:
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J:76005
Gu Y, et al., Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice. J Neurosci. 2002 Apr 1;22(7):2753-63
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:3656053
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Gene symbol:
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Aff2
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Gene name:
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AF4/FMR2 family, member 2
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
3A:
embryonic day 10.5; Aff2tm1Dln/ Aff2tm1Dln
(more  )
Note: The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
Specimen
3A:
(close  )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Aff2tm1Dln/Aff2tm1Dln
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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4% Paraformaldehyde
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Note:
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The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: telencephalon |
Present |
Regionally restricted |
3A
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Expression is present in the ganglionic eminences of the telencephalon, including the lateral and medial ganglionic eminences. There is no staining in most of the rest of the telencephalon.
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Specimen
Not shown:
embryonic day 10.5; Aff2tm1Dln/ Aff2tm1Dln
(more )
Note: The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
Specimen
Not shown:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Aff2tm1Dln/Aff2tm1Dln
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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4% Paraformaldehyde
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Note:
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The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: future spinal cord |
Present |
Single cells |
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Expression is present in some neuroblast cells in the spinal cord.
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Specimen
3B:
embryonic day 12.5; Aff2tm1Dln/ Aff2tm1Dln
(more )
Note: The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
Specimen
3B:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Aff2tm1Dln/Aff2tm1Dln
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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4% Paraformaldehyde
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Note:
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The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: cerebral cortex intermediate zone |
Present |
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3B
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Expression is concentrated in the germinal ventricular zone and the preplate; there are a few expressing cells in the intermediate zone.
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| TS20: cerebral cortex ventricular layer |
Present |
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3B
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Expression is concentrated in the germinal ventricular zone and the preplate; there are a few expressing cells in the intermediate zone.
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| TS20: cortical plate |
Present |
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3B
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Expression is concentrated in the germinal ventricular zone and the preplate; there are a few expressing cells in the intermediate zone.
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Specimen
3C:
embryonic day 15.0-15.5; Aff2tm1Dln/ Aff2tm1Dln
(more )
Note: The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
Specimen
3C:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Aff2tm1Dln/Aff2tm1Dln
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Age:
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embryonic day 15.0-15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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4% Paraformaldehyde
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Note:
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The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
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Specimen
Not shown:
embryonic day 15.0-15.5; Aff2tm1Dln/ Aff2tm1Dln
(more )
Note: The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
Specimen
Not shown:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Aff2tm1Dln/Aff2tm1Dln
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Age:
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embryonic day 15.0-15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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4% Paraformaldehyde
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Note:
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The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: embryo |
Present |
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Under gross examination, expression appears to be present throughout the body. It is especially strong in the head and the extremeties.
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| TS23: head |
Strong |
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Specimen
3D:
postnatal adult; Aff2tm1Dln/ Aff2tm1Dln
(more )
Note: The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
Specimen
3D:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Aff2tm1Dln/Aff2tm1Dln
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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4% Paraformaldehyde
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Note:
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The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
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Specimen
3E:
postnatal adult; Aff2tm1Dln/ Aff2tm1Dln
(more )
Note: The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
Specimen
3E:
(close )
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Genetic Background:
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involves: 129 * C57BL/6
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Mutant Allele(s):
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Aff2tm1Dln/Aff2tm1Dln
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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4% Paraformaldehyde
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Note:
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The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
|
Specimen
Not shown:
postnatal adult; Aff2tm1Dln/ Aff2tm1Dln
(more )
Note: The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
Specimen
Not shown:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
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Mutant Allele(s):
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Aff2tm1Dln/Aff2tm1Dln
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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4% Paraformaldehyde
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Note:
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The authors did not specify the sex of this animal. Since this gene is carried on the X chromosome, it is possible that only one copy of this gene was present in the animal examined.
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