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Gene Expression Data
Assay Details
Assay
Reference: J:103128 Machka C, et al., Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling. Gene Expr Patterns. 2005 Dec;6(1):94-101
Assay type: RNA in situ
MGI Accession ID: MGI:3617193
Gene symbol: Nes
Gene name: nestin
Probe: Nes cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1i: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present 1i
TS17: neural tube Present 1i

Specimen 1j: embryonic day 10.5; Dll1tm1Gos/Dll1tm1Gos (more )
Structure Level Pattern Image Note
TS17: neural tube Weak 1j
TS17: migrating neural crest Present Regionally restricted 1j Segmented expression in neural crest cells is irregular and more restricted in mutant embryos.

Specimen 2i: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present 2i
TS17: neural tube Present 2i

Specimen 2j: embryonic day 10.5; Dll1tm1Gos/Dll1tm1Gos (more )
Structure Level Pattern Image Note
TS17: neural tube Weak 2j
TS17: migrating neural crest Present 2j Expression is detected, but segmented expression is weaker and irregular.

Specimen 2k: embryonic day 10.5; Dll3pu/Dll3+ (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present 2k Expression in this mutant is the same as in wild-type embryos.
TS17: neural tube Present 2k Expression in this mutant is the same as in wild-type embryos.

Specimen 2l: embryonic day 10.5; Jag1Mhdahtu/Jag1Mhdahtu (more )
Structure Level Pattern Image Note
TS17: neural tube Present 2l Expression is slightly reduced compared to wild-type embryos.
TS17: migrating neural crest Present 2l Expression in migrating neural crest cells is slightly reduced compared to wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory