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Gene Expression Data
Assay Details
Assay
Reference: J:49187 Soares HD, et al., Atm expression patterns suggest a contribution from the peripheral nervous system to the phenotype of ataxia-telangiectasia. Neuroscience. 1998 Oct;86(4):1045-54
Assay type: RNA in situ
MGI Accession ID: MGI:3611871
Gene symbol: Atm
Gene name: ataxia telangiectasia mutated
Probe: Atm cDNA5
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen Not Shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nervous system Present Ubiquitous expression with high levels in mitotically active cell populations.
TS19: cerebellum primordium Present

Specimen 2 A1,A2: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebellum Present 2A2 , 2A1
TS21: midbrain Present Regionally restricted 2A2 , 2A1 Expression is in the caudalmost part.

Specimen 2 B1,B2, 3: postnatal day 7 (more )
Note: Figure 3 is a higher magnification of Figure 2B1.
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Present 2B1 , 2B2 , 3
TS28: cerebellum white matter Present 2B1 , 2B2 , 3
TS28: cerebellum external granule cell layer Present Regionally restricted 2B1 , 3 , 2B2 Expression is in the proliferative zone with lower levels throughout the premigratory zone.

Specimen 2 C1,C2: postnatal week 6-8 (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Weak 2C2 , 2C1
TS28: cerebellum Purkinje cell layer Absent 2C2 , 2C1
TS28: cerebellum molecular layer Absent 2C2 , 2C1

Specimen 4 A1,A2: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Strong 4A2 , 4A1
TS21: corpus striatum Strong 4A2 , 4A1
TS21: thalamus Strong 4A2 , 4A1
TS21: forebrain Strong Regionally restricted 4A2 , 4A1 Expression is in germinal neuroepithelia zones. Expression is in the hippocampus.

Specimen 4 B1,B2: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 4B2 , 4B1
TS28: corpus striatum Present 4B2 , 4B1
TS28: hippocampus Present 4B2 , 4B1
TS28: thalamus Present 4B2 , 4B1

Specimen 4 C1,C2: postnatal week 6-8 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 4C1 , 4C2
TS28: cerebral cortex Trace 4C1 , 4C2
TS28: corpus striatum Trace 4C1 , 4C2
TS28: thalamus Trace 4C1 , 4C2

Specimen 5 A1,A2: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dorsal root ganglion Strong 5A2 , 5A1

Specimen 5 B1,B2: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: dorsal root ganglion Present 5B1 , 5B2
TS27: spinal cord Present 5B1 , 5B2

Specimen 5 C1,C2: postnatal week 6-8 (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Very strong Regionally restricted 5C2 , 5C1 Expression is in sensory neurons and satellite cells.

Specimen 6A: postnatal week 6-8 (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Single cells 6A Expression is in both sensory neurons and satellite cells, absent in Schwann cells.

Specimen 6B: postnatal week 6-8 (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Single cells 6B Expression is in sensory neurons, some with high signal and some with low signal.

Specimen 6C: postnatal week 6-8 (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Single cells 6C Expression is in sensory neurons, some with high signal and some with low signal.
TS28: thalamus Present 6C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory