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Gene Expression Data
Assay Details
Assay
Reference: J:85472 Kawahira H, et al., Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development. 2003 Oct;130(20):4871-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3608777
Gene symbol: Hhip
Gene name: Hedgehog-interacting protein
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 12.5; Hhiptm1Amc/Hhip+ (more )
Structure Level Pattern Image Note
TS20: midgut derived duodenum Strong 1A
TS20: stomach Strong 1A
TS20: pancreas Absent 1A

Specimen 1C: embryonic day 18.5; Hhiptm1Amc/Hhip+ (more )
Structure Level Pattern Image Note
TS26: duodenum Strong 1C
TS26: stomach Strong 1C
TS26: pancreas Absent 1C

Specimen 1E: postnatal adult; Hhiptm1Amc/Hhip+ (more )
Structure Level Pattern Image Note
TS28: duodenum Strong 1E
TS28: stomach Strong 1E
TS28: pancreas Absent 1E Macroscopic analysis did not reveal expression in adult pancreatic tissue.

Specimen 1F: postnatal adult; Hhiptm1Amc/Hhip+ (more )
Structure Level Pattern Image Note
TS28: islets of Langerhans Weak 1F Analysis of sectioned adult tissue showed low levels of expression within pancreatic islets.

Specimen 2A: embryonic day 12.5; Hhiptm1Amc/Hhip+ (more )
Structure Level Pattern Image Note
TS20: midgut derived duodenum Present 2A
TS20: stomach Present 2A

Specimen 2B: embryonic day 12.5; Hhiptm1Amc/Hhiptm1Amc (more )
Structure Level Pattern Image Note
TS20: midgut derived duodenum Strong 2B Expression in the homozygote is signficantly increased relative to what is seen in the heterozygote.
TS20: stomach Strong 2B Expression in the homozygote is signficantly increased relative to what is seen in the heterozygote.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory