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Gene Expression Data
Assay Details
Assay
Reference: J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
Assay type: RNA in situ
MGI Accession ID: MGI:3585621
Gene symbol: Ccnd1
Gene name: cyclin D1
Probe: UI-M-BH3-asm-e-05-0-UI.s1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: This data is from Supplemental Table 5, Gene column, row: 22288 cyclin D1. After cryosectioning, tissue was fixed for 10' in 4% paraformaldehyde prior to processing.
Results
Specimen E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present Regionally restricted Expression was detected in the outer neuroblastic layer.

Specimen E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present Regionally restricted S4_Cyclin D1 E14 , S3_Cyclin D1 E14 , Submitted Image - CyclinD1e14 , S11_Cyclin D1 E14 , 5B Cyclin D1 E14 , 2(Continued)B Cyclin D1 E14 , 2A Cyclin D1 E14 Expression was detected in the outer neuroblastic layer but was strong in a subset of cells in the outer neuroblastic layer.

Specimen E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: retina nuclear layer Present Regionally restricted S3_Cyclin D1 E16 , Submitted Image - CyclinD1e16high , S4_Cyclin D1 E16 , S11_Cyclin D1 E16 , Submitted Image - CyclinD1e16 , 5B Cyclin D1 E16 , 2A Cyclin D1 E16 , 2(Continued)B Cyclin D1 E16 Expression was detected in the outer neuroblastic layer but was higher in a subset of cells.

Specimen E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: retina outer nuclear layer Present 2(Continued)B Cyclin D1 E18 , 2A Cyclin D1 E18 , Submitted Image - CyclinD1e18 , S3_Cyclin D1 E18 , 5B Cyclin D1 E18 , S11_Cyclin D1 E18 , S4_Cyclin D1 E18 Expression was detected in the outer neuroblastic layer but was higher in a subset of cells.

Specimen P0/1: postnatal day 0-1 (more )
Structure Level Pattern Image Note
TS27: retina outer nuclear layer Present Regionally restricted S11_Cyclin D1 P0 , S4_Cyclin D1 P0 , 5B Cyclin D1 P0 , 2(Continued)B Cyclin D1 P0 , Submitted Image - CyclinD1p1 , S3_Cyclin D1 P0 , 2A Cyclin D1 P0 , Submitted Image - CyclinD1p0 Expression was detected in a subset of cells in the vitreal outer neuroblastic layer.
TS27: retina inner nuclear layer Present Regionally restricted S11_Cyclin D1 P0 , Submitted Image - CyclinD1p1 , 2(Continued)B Cyclin D1 P0 , S4_Cyclin D1 P0 , S3_Cyclin D1 P0 , 5B Cyclin D1 P0 , Submitted Image - CyclinD1p0 , 2A Cyclin D1 P0 Expression was detected in a subset of cells in the vitreal inner neuroblastic layer.

Specimen P2/3: postnatal day 2-3 (more )
Structure Level Pattern Image Note
TS27: retina outer nuclear layer Present Regionally restricted 5B Cyclin D1 P2 , Submitted Image - CyclinD1p3 , S4_Cyclin D1 P2 , S11_Cyclin D1 P2 , 2A Cyclin D1 P2 , 2(Continued)B Cyclin D1 P2 , S3_Cyclin D1 P2 Expression was detected in a subset of cells (none in the center) in the vitreal outer neuroblastic layer.
TS27: retina inner nuclear layer Present Regionally restricted S4_Cyclin D1 P2 , S3_Cyclin D1 P2 , S11_Cyclin D1 P2 , 2A Cyclin D1 P2 , 5B Cyclin D1 P2 , Submitted Image - CyclinD1p3 , 2(Continued)B Cyclin D1 P2 Expression was detected in a subset of cells in the vitreal inner neuroblastic layer.

Specimen P6/7: postnatal day 6-7 (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted Submitted Image - CyclinD1p6per , 2A Cyclin D1 P6 , 2(Continued)B Cyclin D1 P6 , S4_Cyclin D1 P6 , 5B Cyclin D1 P6 , Submitted Image - CyclinD1p6center , S3_Cyclin D1 P6 , S11_Cyclin D1 P6 Expression was detected in a subset of the inner nuclear layer at the edge.
TS28: retina ganglion cell layer Present Regionally restricted Submitted Image - CyclinD1p6per , 2A Cyclin D1 P6 , S11_Cyclin D1 P6 , 5B Cyclin D1 P6 , 2(Continued)B Cyclin D1 P6 , S4_Cyclin D1 P6 , S3_Cyclin D1 P6 , Submitted Image - CyclinD1p6center Expression was detected in ganglion cells at the edge.

Specimen P8/10: postnatal day 8-10 (more )
Structure Level Pattern Image Note
TS28: retina Absent Submitted Image - CyclinD1p8per , Submitted Image - CyclinD1p8center

Specimen Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina Absent 2(Continued)B Cyclin D1 Adult , Submitted Image - CyclinD1adult , S4_Cyclin D1 Adult , S11_Cyclin D1 Adult , 2A Cyclin D1 Adult , 5B Cyclin D1 Adult , S3_Cyclin D1 Adult

Specimen CNS: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: central nervous system Absent

Specimen Embryo: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: central nervous system Strong Regionally restricted Expression was detected in a subset of ventral CNS progenitors.
TS22: dorsal root ganglion Strong


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory